RI Strains

RI Strains

See BXD Residuals Spreadsheet						B <62,000)				t dist, 2-tailed, p=0.025 per tail)										<425 = D type	Proximal Chr 11: D11Mit2, D11Byu1
BXD RI Strains	Neurons	SEM	SD	CV	N	RGC_Class1*	RGC_Class2**	Tstap91A	Z	95%CI-	95%CI+	Lowest	Highest	Range	SD_Range	Age	Body	Brain	BrainSE	BrainSD	BrainCV	BrainN	Brain_Class	D11Ncvs74	Belknap_BXD
C57BL/6J	54,320	+/-1,347	+/-5,216	9.60%	16	B	B	B	-1	51,465	57,175	47,070	65,653	18,582	+/-5,853	79	21.5	472	+/-5.3	+/-29	6.10%	31	B	B	465

BXD1	61,996	+/-1,077	+/-3,231	5.20%	10	U	U	B	0.7	59,596	64,396	59,552	67,167	7,615	+/-2,673	51	20.5	448	+/-6.9	+/-23	5.10%	12	B	B	450
BXD2	66,063	+/-1,644	+/-3,677	5.60%	6	D	D	D	1.61	62,039	70,087	60,417	70,774	10,358	+/-4,091	53	23.1	427	+/-8.2	+/-18	4.30%	6	B	B	390
BXD5	75,548	+/-1,273	+/-2,846	3.80%	6	D	D	D	3.72	72,433	78,662	72,566	79,857	7,291	+/-2,880	63	18.9	514	+/-8.7	+/-23	4.50%	8	B	B	477
BXD6	62,695	+/-801	+/-1,961	3.10%	7	D	D	D	0.86	60,802	64,588	59,911	64,712	4,801	+/-1,776	163	19.8	392	+/-3.6	+/-9	2.40%	8	D	D	361
BXD8	60,153	+/-1,433	+/-2,026	3.40%	3	B	U	D	0.29	55,592	64,713	57,856	61,691	3,834	+/-1,419	259	21.1	430	+/-3.6	+/-11	2.50%	10	B	B	421
BXD9	66,053	+/-1,611	+/-3,602	5.50%	6	D	D	D	1.6	62,112	69,995	61,325	69,342	8,017	+/-3,167	185	22.8	439	+/-11.3	+/-16	3.60%	3	B	B	419
BXD11	60,819	+/-1,451	+/-4,104	6.70%	9	B	U	B	0.44	57,537	64,101	56,124	66,474	10,351	+/-4,089	66	19.7	430	+/-4.0	+/-12	2.80%	10	B	B	NA
BXD12	54,788	+/-943	+/-1,886	3.40%	5	B	B	B	-0.9	52,365	57,211	53,045	57,857	4,813	+/-2,069	37	18.1	408	+/-6.4	+/-6	1.60%	2	D	B	412
BXD13	54,101	+/-2,086	+/-4,171	7.70%	5	B	B	B	-1.05	48,740	59,462	56,328	58,053	1,725	+/-1,019	27	18.6	402	+/-4.5	+/-9	2.20%	5	D	D	403
BXD14	65,283	+/-1,628	+/-3,987	6.10%	7	D	D	D	1.43	61,434	69,132	59,564	70,267	10,704	+/-3,960	68	21.8	436	+/-6.0	+/-15	3.40%	7	B	D	439
BXD15	64,235	+/-989	+/-2,211	3.40%	6	D	U	D	1.2	61,816	66,655	61,004	67,213	6,208	+/-2,452	100	23.4	442	+/-9.4	+/-21	4.80%	6	B	B	429
BXD16	64,255	+/-2,517	+/-6,166	9.60%	7	D	U	D	1.2	58,303	70,208	55,934	75,614	19,680	+/-7,773	64	21.4	465	+/-7.4	+/-20	4.20%	8	B	B	436
BXD18	54,266	+/-1,147	+/-2,565	4.70%	6	B	B	B	-1.02	51,459	57,072	50,627	58,177	7,551	+/-2,983	113	20.3	413	+/-8.0	+/-14	3.30%	4	D	D	427
BXD19	67,558	+/-1,581	+/-4,337	6.40%	9	D	D	D	1.94	63,981	71,135	61,653	74,741	13,089	+/-4,411	108	19.5	423	+/-6.7	+/-19	4.50%	9	B	B	NA
BXD20	62,184	+/-1,382	+/-3,909	6.30%	9	U	U	D	0.74	59,058	65,310	55,879	68,289	12,410	+/-4,356	71	17.7	380	+/-3.9	+/-13	3.40%	12	D	D	NA
BXD21	59,968	+/-1,422	+/-3,763	6.30%	8	B	U	D	0.25	56,688	63,248	54,618	64,885	10,267	+/-3,799	114	24.8	449	+/-7.3	+/-19	4.30%	8	B	B	409
BXD22	64,802	+/-1,869	+/-3,738	5.80%	5	D	D	D	1.33	59,997	69,607	60,994	70,785	9,790	+/-4,210	38	17.3	430	+/-5.4	+/-11	2.50%	5	B	B	431
BXD23	54,535	+/-1,981	+/-4,429	8.10%	6	B	B	B	-0.96	49,689	59,381	50,750	60,873	10,123	+/-3,999	86	19.6	421	+/-8.0	+/-18	4.30%	6	D	B	432
BXD24	62,395	+/-992	+/-2,429	3.90%	7	D	U	D	0.79	60,050	64,739	58,714	65,631	6,917	+/-2,559	267	23.5	413	+/-6.9	+/-18	4.40%	8	D	D	380
BXD25	54,759	+/-1,418	+/-3,171	5.80%	6	B	B	B	-0.91	51,288	58,229	53,110	58,753	5,643	+/-2,229	60	17.8	409	+/-5.5	+/-13	3.30%	7	D	B	394
BXD27	51,568	+/-1,391	+/-3,110	6.00%	6	B	B	B	-1.62	48,165	54,971	48,194	55,662	7,468	+/-2,950	41	15.5	365	+/-6.9	+/-15	4.20%	6	D	D	381
BXD28	53,864	+/-3,624	+/-7,249	13.50%	5	B	B	B	-1.11	44,548	63,181	44,367	60,534	16,167	+/-7,857	56	18.9	405	+/-7.7	+/-17	4.30%	6	D	D	389
BXD29	63,539	+/-1,859	+/-4,156	6.50%	6	D	U	D	1.05	58,991	68,087	58,132	69,862	11,729	+/-4,633	65	19.7	398	+/-8.0	+/-18	4.50%	6	D	D	375
BXD30	68,079	+/-2,154	+/-4,816	7.10%	6	D	D	D	2.06	62,809	73,349	61,398	72,960	11,562	+/-4,971	55	18.4	377	+/-5.6	+/-14	3.60%	7	D	D	NA
BXD31	66,833	+/-2,038	+/-4,556	6.80%	6	D	D	B	1.78	61,848	71,819	59,184	71,842	12,659	+/-5,000	51	21.3	415	+/-6.9	+/-15	3.70%	6	D	D	NA
BXD32	76,836	+/-3,355	+/-7,502	9.80%	6	D	D	D	4	68,626	85,046	67,181	85,632	18,451	+/-7,934	47	19.6	429	+/-2.6	+/-11	2.50%	18	B	D	NA

DBA/2J	63,351	+/-1,137	+/-4,100	6.50%	13	D	D	D	1	60,894	65,807	57,625	69,775	12,150	+/-3,730	52	17	394	+/-7.6	+/-23	5.80%	10	D	D	339

Average	61,959	58,835	+/-3,831	6.17%	6.5	*Liberal	**Stringent							9,585	+/-3,818	89	20.1	422		+/-16	3.60%			F=14.77, p-.00083 with D11Ncvs74	413
Count	28	26	766	0.46%	168			No alternative							correl with RGC	0.017	0.259	0.489	0.24					426	+/-29
SD across BXD	+/-4,498			2.37%			Tstap91A (at 45 cM, 2 cM distal to Hoxb)	Jan 18 1996 QT Map Manager Links report							correl with brain	0.06	0.444	—						r=	0.82
Average D type	65,467	15		5.10%			F=	27.65 (with truncation of BXD5, and 32 to 68,000
Average B type	54,754	8		5.50%			p=	0.0000217	2 in 100,000						r crit 5% with 20 df is 0.423
Average all BXDs	62,199	23		5.30%	0.7185629		approx lod	4.6							if r=.443 then z = 0.475
F (Nov 95) of 18.7 with 25 and 156 df

BXH RI Strains	Neurons	SEM	SD	CV	N	RGC_Class1*	Chr 2, Hdc	Chr 11 Mpmv4 (48 cM)	Z	95%CI-	95%CI+	Lowest	Highest	Range	SD_Range	Age	Body	Brain	BrainSE	BrainSD	BrainCV	BrainN	Brain_Class
C57BL/6J	54,320	1,347	5,216	9.60%	16	B	B		-1	51,465	57,175	47,070	65,653	18,582	+/-5,853	79	19.5	465		+/-29	6.20%

BXH2	63,406	4,397	4,397	6.90%	2	H	B	H		44,486	82,327					42	19	414	+/-1	+/-1	0.30%	2	B
BXH3	59,642				1	U	B	H								47	20	461	+/-15	+/-15	3.30%	2	H
BXH4	68,666	2,282	3,227	4.70%	3	H	H	H		61,404	75,929					60	21	479	+/-14	+/-25	5.20%	4	H
BXH6	51,926	1,627	2,818	5.40%	4	B	B	H		47,409	56,443					68	18	450	+/-8	+/-15	3.20%	4	B
BXH7	60,779				1	U	B	H								38	17	448	+/-0	+/-0	0.10%	2	B
BXH8	64,631				1	H	H	H								27	12	395	+/-1	+/-1	0.20%	2	B
BXH9	56,967	2,238	3,876	6.80%	4	B	B	B		50,754	63,180					72	24	477	+/-3	+/-5	1.10%	4	H
BXH10	64,931				1	H	H	B								35	18	448	+/-19	+/-19	4.20%	2	B
BXH11	51,312				1	B	B	B								54	20	422				1	B
BXH12	69,674	791	1,369	2.00%	4	H	H	H		67,479	71,869	68,179	71,498	3,319		58	19	432	+/-3	+/-4	1.00%	3	B
BXH14	66,023	3,297	7,372	11.20%	6	H	H	H		57,956	74,091	54,231	72,980	18,749		51	19	421	+/-4	+/-9	2.10%	6	B
BXH19	54,136	2,660	4,608	8.50%	4	B	B	B		46,749	61,522	48,761	59,761	11,000		44	18	432	+/-13	+/-22	5.00%	4	B

C3H/HeJ	67,039	+/-1,625	+/-3,634	5.40%	6	H	H			63,063	71,015	59,061	71,259	12,197	+/-3,842	88	30	510	+/-4	+/-6	1.20%	3	H

Midpoint	60,679				32	Linkage stats of Jan 24 96:	best QTL match to Hdc on Chr 2 (p=0.001, F=20.9)											440	+/-8	+/-30	2.50%		No locus on Chr 11 with this pattern.
Count	12
SD across BXH	6,290
Average H type	68,121
Average B type	54,138
Average all BXHs	61,008

							t dist, 2-tailed, p<0.025 per tail)