Project 1: The Mouse Brain Library Project 2: Internet Microscopy (iScope) Project 3: Neurocartographer and Segmentation of the MBL Project 4: The Neurogenetics Tool Box
















Principal Investigator/Program Director Williams, Robert W.


Aim 4. Create Image Analysis Tools.

The usefulness of the MBL as a tool for the investigation of neuroanatomical QTLs lies not only in the ability to search and manipulate images, but in the ease of analysis. Toward that end, we will develop systems for direct web-based analysis of images using modifications and extensions of Image/J, a free Java image analysis program. We will allow fast morphometry and image enhancement of the MBL collection. For off-line analysis, we will provide hooks and tutorials that explain how to use other popular image analysis packages, including NeuroZoom and NIH Image. We will also integrate data sets from the NeuroCartographer Project (Project 3) to aid in screening and analysis of the MBL. For example, once the MBL collection has been fully segmented it will be possible to call up specific sections simply by defining an ROI. This hybridization between Projects 1 and 3 will require the construction of special relational databases.





Status of Current Research Efforts