Sym_mouse 0: Chr_mouse Alias Search_sym Sort_by_mouse_sym Map_ccr Map_mit Chr_band Locus_name Map_method Sym_human Chr_human Chr_hs_guess Comment Reference Ref_ccr Anchor_comp Chr_cat Chr_cow Chr_deermus Chr_dog Chr_fox Chr_hamster Chr_horse Chr_mink Chr_mouse_predicted Chr_pig Chr_rabbit Chr_rat Chr_sheep Comp_note Cosmid_hsa Cosmid_mmu Enzyme Genbank Gene_note Is_129 Is_a Is_akr Is_balbc Is_c3h Is_c57bl6 Is_dba2 Is_sjl Locus_type Map_gbase Map_cm_hsa Map_mb_has Flpter_hsa Map_note Map_panel Mit_a Mit_akr Mit_assay Mit_c57bl6 Mit_balbc Mit_c3h Mit_cast Mit_dba2 Mit_ob Mit_lp Mit_nod Mit_non Mit_spr Neighbor_cen Neighbor_tel Panel_name Phenotype Primer Repeat_info Ri_axb_bxa Ri_akxd Ri_akxl Ri_bxd Ri_bxh Ri_bxj Ri_cxb Ri_cxj Ri_cxs Ri_lxp Ri_nx8 Ri_nx9 Ri_nxsm Ri_oxa Ri_swxj Ri_swxl Yac_hsa Yac_mmu Year Sort_by_group Sort_by_human_chr Sort_by_human_sym Status 3/31/93 12/1/94 Jax_number Accession_mdb A000001 Aap UN aap Aap active avoidance performance Poor in DBA/2J, good in C57BL/6J. DBA allele is dominant. Probably not a single gene. Peeler 1987 Behav Neural Biol 48:83 brain (unclassified); behavior (unclassified) 1987 polygenic 8/10/94 R109346 Aat2 UN Aat-2, Alpha-1 PI-2 aat2 Aat002 alpha 1 antitrypsin 2 Title of PNAS paper by Borriello & Krauter 1991: Multiple murine alpha-1 protease inhibitor gens show unusual evolutionary divergence. Borriello F 1991 PNAS 88:9417 M75716 1300 nt mRNA 3' end. D enzyme (unclassified) 1991 RW personal 8/10/94 R109347 abn UN abn abn abnormal Author ?? 1970 Mouse News Lett 43:57 development (unclassified) provisional, extinct? 8/10/94 5/22/94 R109348 ac UN 'ac' ac absent corpus callosum Noted first in rodless mice. BALB/cJ and 129/J strain have similar phenotype. Probably not a single gene. Should be withdrawn. Wahlsten 1982 J Hered 73:281 V brain (cortex, axon) 1982 polygenic, withdraw? 8/10/94 R109349 Acas UN Acs acas, acs Acas acyl-coenzyme A sythetase Weiner 1991 J Biol Chem 264:11945 enzyme (synthetase) 1991 8/10/94 R109351 Acc UN acc Acc anterior capsular cataract eye (lens or cataract) provisional 8/10/94 R109352 Ack UN ack, acm ack, acm Ack anti C. kutscheri Influences efficiency of phagocytes against C. kutscheri. immune (virus or disease or tumor resistance) 8/10/94 R109354 Acre UN acre Acre acetylcholine receptor, epsilon Gardner 1990 Nucleic Acids Res 18:6714 D protein (receptor) 1990 8/10/94 R109355 act UN act act adult cataract Author ?? 1972 Mouse News Lett 47:19 eye (lens or cataract) extinct? 8/10/94 5/22/94 R109356 Actg-ps1 UN actgps1 Actgps001 actin, gamma, pseudogene 1 Man 1987 Nucleic Acid Res 15:3291 & Yoda K 1989 Biochimica Biophysica Acta 1009:194 X13051, X16348 L1Md-14RH1 repetitive sequence. *Title* A duplicated region of the mouse genome containing a cytoplasmic gamma actin processed pseudogene associated with long interspersed repetitive elements D DNA (pseudogene); protein (structural) 1987 8/10/94 R109357 Actg-ps2 UN actgps2 Actgps002 actin, gamma, pseudogene 2 Begg 1988 J Mol Biol 203:677 X13050 L1Md-14RH2 repetitive sequence. *Title* A duplicated region of the mouse genome containing a cytoplasmic gamma actin processed pseudogene associated with long interspersed repetitive elements D DNA (pseudogene), protein (structural) 1988 8/10/94 R109358 Actvs UN actvs Actvs actin, alpha, vascular smooth muscle Min B1988 Nucleic Acids Res 16:10374 & Min B 1990 J Bio Chem 265:16667 M57409, X13297, X13839 (Hsa) protein (structural), viscera (heart or vessels), muscle 1988 8/10/94 8/28/94 R109359 Actx UN actx Actx melanoma X-actin Sadano 1988 J Biol Chem 263:15868 protein (structural) 1988 8/10/94 R109360 Acvr1 UN ActR, Acvr acrv1, acvr, actr Acrv001 activin receptor type 1 Hom ACRV1 11q23-q24 Human gene that may have murine homolog; probably on Chr 9. Intraacrosomal protein SP-10 gene. Probably a serine kinase. Matthews LS 1991 Cell 65:973 & Golden WL 1993 Genomics 18:416 M65287 M65287: 2563 bp mRNA sequence. protein (receptor) 1991 RW personal 8/10/94 8/20/94 R109361, R111542 Acvr2b UN ActRIIB acvr2b, actr2b, actriib Acvr002b activin receptor type 2b Expressed early in development. One of at least two activin receptor types. Attisano L 1992 Cell 68:97 M84120, M84119 activin receptor (ActR IIB) mRNA, complete cds. *Title* Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors protein (receptor) 1992 8/10/94 8/20/94 R109362 Acy2 UN Acy-2 acy2 Acy002 aminoacylase 2 Nadeau 1986 Genet Res 48:175 enzyme (unclassified) 1986 8/10/94 11/10/94 R109363 Adcy6 UN Adcyc-6, MUSADCYC, Ak-6? adcy6, adcyc6, ak6 Adcyc006 adenylyl cyclase 6 A calcium-inhibitable adenylyl cyclase from NCB-20 cells. Is this a new member of the Ak series (Ak-6?). Yoshimura M 1992 PNAS 89:6716 M93422 enzyme (cyclase 1992 old RW personal 8/10/94 R109364 ADHir UN adhir ADHir inducibility by ethanol of alcohol dehydrogenase in liver r * * i * r * * unclassified 1992 provisional 8/10/94 R109365 Adora1 UN adora1, 'a1' Adora001 adenosine A1 receptor A1 22q11-q11 Marquardt 1994 J Immunol 152:4508 &Libert F 1991 Genomics 11:225 1991 8/10/94 9/18/94 R113701 Adora2a UN adora2a Adora002a adenosine A2a receptor 22q11.2-q13.1 Marquardt 1994 J Immunol 152:4508 MacCollin M 1994 Genomics 20:332-333. 1994 8/10/94 9/18/94 R113702 Adora2b UN adora2b Adora002b adenosine A2b receptor Marquardt 1994 J Immunol 152:4508 1994 8/10/94 08/05/94 R113703 Adp UN adp Adp acrodysplasia skeleton (unclassified) 1993 8/10/94 R109366 Ads2 UN Ads-2 ads2 Ads002 anti-dsDNA antibody 2 immune (antibody) 8/10/94 R109369 Ads4 UN Ads-4 ads4 Ads004 anti-dsDNA antibody 4 immune (antibody) 8/10/94 R109370 Adss1 UN Adss adss1 Adss001 adenylosuccinate synthetase 1 Guicherit 1991 J Biol Chem 266:22582 enzyme (synthethase) 1991 8/10/94 3/23/94 R109371 Adss2 UN adss2 Adss002 adenylosuccinate synthetase 2 Guicherit 1994 J Biol Chem 269:4488 enzyme (synthethase) 1994 8/10/94 10/16/94 R114344 Afr2 UN Afr-2, rif afr2, rif Afr002 alpha fetoprotein regulation 2 Inducibility. protein (regulatory) 8/10/94 R109372 Agat UN agat Agat O-6-alkylguanine DNA alkyltransferase Santibanez-Koref 1992 Mol Carcinogen 5:161 enzyme (DNA or RNA processing, transferase) 1992 8/10/94 R109373 Agtr1a UN Agtr-1a, Angtr-1a, AT1 agtr1a, angtr1a, at1 Agtr001a angiotensin receptor 1a Bernstein KE 1993 Am J Kidney Dis 22:745 protein (receptor) 1993 8/10/94 R109374 Agtr1b UN Agtr-1b, Angtr-1b, AT1 agtr1b, angtr1b, at1 Agtr001b angiotensin receptor 1b protein (receptor) 8/10/94 R109375 Agtr2 UN AT2 agtr2, at2 Agtr002 angiotensin II, receptor type 2 Ichiki 1994 Biochim Biophys Acta 1189:247 1994 8/10/94 R109376 aha UN aha aha autoimmune hemolytic anemia blood (anemia); immune (immune defect) provisional 8/10/94 R109377 Ahr2 UN Ahr-2 ahr2 Ahr002 aldehyde reductase 2 Hexonate dehydrogenase. enzyme (reductase) 8/10/94 R109380 Ahr4 UN Ahr-4 ahr4 Ahr004 aldehyde reductase 4, liver and kidney A? a? a? a? * b b * enzyme (reductase) 8/10/94 R109381 Aia2 UN Aia-2 aia2 Aia002 autoimmune hemolytic anemia 2 blood (anemia); immune (immune defect) 8/10/94 R109382 Aigf UN aigf Aigf androgen induced growth factor Tanaka 1992 PNAS 89:8928 protein (growth factor, hormone) 1992 8/10/94 R109383 Ak4 UN Ak-4 ak4 Ak004 adenylate kinase 4 B enzyme (kinase) 8/10/94 R109385 Akp-ps1 UN akpps1 Akpps001 alkaline phosphatase, pseudogene 1 D enzyme (phosphatase), development (unclassified) 8/10/94 R109386 Akvp UN akvp Akvp AKR leukemia virus protein inducer May be the same as Akv-3/Emv-13 locus. immune (virus or disease or tumor resistance) 8/10/94 R109387 Aldh2 UN Ahd5, Ahd-5 aldh2, ahd5, aldh5 Aldh002 aldehyde dehydrogenase 2, mitochondrial (class 2) ALDH2 Mouse symbol revised Aug 94 to conform to other mammals. Holmes RS 1994 personal communication X14977 (Rno), Y00109 (Hsa) enzyme (dehydrogenase) 1994 provisional 8/10/94 8/28/94 R109379 Aldh4r UN Aldh4-r, Ahd3r, Ahd-3r aldh4r, ahd3r, aldh3 Aldh004r aldehyde dehydrogenase 4, liver microsomal, regulator Holmes RS 1994 personal communication Aldh4 itself now mapped to Chr 11. This locus may map to Chr 3. enzyme (dehydrogenase) 8/10/94 8/27/94 R109378 Alm UN alm Alm anterior lenticonus with microphthalmia Heteros have microophthalmia, white belly spot and are small. color; eye (lens or cataract); endocrine (growth or obesity) provisional 8/10/94 R109389 ALMR UN almr ALMR name unknown R Listed in Map Manager 2.4 files, Aug 1993. Not listed in GBASE, July 1993. Datta 1982 J Immunol 129:1539 unclassified 8 8 8 N N U U 8 8 N 8 N N 1982 8/10/94 R109390 alp UN alp alp alopecie hair provisional, extinct 8/10/94 R109391 Amd1 UN Amd-1 amd1 Amd001 s-adenosylmethionine decarboxylase 1 Also apparently referred to as SAM decarboxylase. 4.1.1.50 M34464 (Rno), M21154 (Hsa) enzyme (decarboxylase) 8/10/94 9/10/94 R109392 Amh-rs3 UN amhrs3 Amhrs003 anti-Mullerian hormone, related sequence 3 R DNA (pseudogene or related sequence); endocrine (hormone related); endocrine (hormone); reproduction (duct related) S N N N S N N N S N N S N S S N N 8/10/94 R109393 Amh-rs6 UN amhrs6 Amhrs006 anti-Mullerian hormone, related sequence 6 R DNA (pseudogene or related sequence); endocrine (hormone related); endocrine (hormone); reproduction (duct related) N S S S S N S S N N S S N N S N S 8/10/94 R109394 Amh-rs8 UN amhrs8 Amhrs008 anti-Mullerian hormone, related sequence 8 R DNA (pseudogene or related sequence); endocrine (hormone related); endocrine (hormone); reproduction (duct related) N S N S N S N N N S S S N N S S N 8/10/94 R109395 Ams UN ams Ams s-adenosylmethionine synthetase Sakata 1993 J Biol Chem 268:13978 8/10/94 R109396 Angtr2a UN Angtr-2a, Agtr-2a, AT2 angtr2a, agtr2a, at2 Angtr002a angiotensin 2, receptor a Probably needs the new symbol Agtr-2a to be consistent with other recent(1993) changes in related loci. Listed in Peters and Cocking, Mouse Genome 91:162. Sasamura 1992 Biochem Biophy Res Comm 185:253 & Ichiki 1994 Biochim Biophys Acta 1189:247 L32840 mRNA sequence, 1291 bp. protein (receptor); endocrine (hormone 1992 nomenclature 8/10/94 7/20/94 R109397 Anth UN anth Anth resistance to Bacillus anthracis immune (virus or disease or tumor resistance) provisional 8/10/94 R109398 Anx7 UN anx7 Anx007 annexin 7 Annexin VII. 1993 8/10/94 R109399 ao UN 'ao' ao apampischo Homozygotes loose hair starting at P10. Loss moves rostro-caudally. New coat is rougher, thinner, and darker. VanPelt 1969 J Hered 60:79 hair 1969 8/10/94 R109400 Aop1 UN D0Tohi1 aop1, d0tohi1 Aop001 anti-oxidant protein 1 Obinata M 1994 personal communication 1994 8/10/94 R109401 ap UN 'ap' ap alopecia periodica hair extinct 8/10/94 R109402 Ap2tf UN ap2tf Ap002tf adipocyte protein 2 transcription factor Mitchell 1991 Gene Develop 5:105 1993 8/10/94 R109403 Apcat1 UN Apcat-1, Apc-1, Apyc, Anc, Pcs-2 apcat1, apc1, acp1, anc, apyc, pcs2 Apcat001 anterior polar cataract 1 4 alleles, numbered 1 to 4. Allele 2 was once known as "anisocoria" locus. Homozygotes have not been recovered. Ovoid pupils, cataracts in 20% of cases. Kratochvilova 1990 Mouse Genome 86:249 eye (lens or cataract); lethality (unclassified) 1990 8/10/94 R109404 Aplp1 UN aplp1 Aplp001 amyloid beta (A4) precursor-like protein 1 Not the same as Appl1. Wasco 1992 PNAS 89:10758 1992 8/10/94 R109406 Apo UN apo Apo anterior polar opacity Author 1983 Mouse News Lett 68:86 eye (lens or cataract) provisional 8/10/94 5/22/94 R109407 Apoc UN Apoc apoc Apoc anterior polar cataract Listed in Mouse Genome 91. Not listed in GBASE July 1993 with this name. Not the same as apolipoprotein C locus. eye (lens or cataract) provisional 8/10/94 R109408 Arbp UN arbp Arbp acidic ribosomal phosphoprotein PO X15267, M17885 (Hsa) enzyme (DNA or RNA processing) 8/10/94 8/28/94 R109410 Arf1 UN Arf arf1, arf Arf001 ADP-ribosylation factor Schurmann 1994 J Biol Chem 269:15683 1994 provisional 8/10/94 8/5/94 R109412 Arf2 UN arf2 Arf002 ADP ribosylation factor 2 Schurmann 1994 J Biol Chem 269:15683-15688 1994 8/27/94 R113922 Arf3 UN arf3 Arf003 ADP-ribosylation factor 3 Schurmann 1994 J Biol Chem 269:15683 1994 8/10/94 08/05/94 R113704 Arf4 UN arf4 Arf004 ADP-ribosylation factor 4 Schurmann 1994 J Biol Chem 269:15683 1994 8/10/94 08/05/94 R113705 Arf5 UN arf5 Arf005 ADP-ribosylation factor 5 Schurmann 1994 J Biol Chem 269:15683 1994 8/10/94 08/05/94 R113706 Arf6 UN arf6 Arf006 ADP-ribosylation factor 6 Schurmann 1994 J Biol Chem 269:15683 1994 8/10/94 08/05/94 R113707 Arg1 UN Arg-1 arg1 Arg001 arginase 1, liver Ohtake 1987 Biochem Biophys Res Comm 146:1064 J02720 (Rno), M14502 (Hsa) 1987 8/10/94 8/29/94 R109413 Arl1 UN arl1 Arl001 ADP-ribosylation-like 1 Schurmann 1994 J Biol Chem 269:15683 1994 8/10/94 08/05/94 R113708 Arl4 UN arl4 Arl004 ADP-ribosylation-like 4 Schurmann 1994 J Biol Chem 269:15683 1994 8/10/94 08/05/94 R113709 As2-ps1 UN as2ps1 As002 ps001 arylsulfatase A, pseudogene 1 Kreysing 1994 Genomics 19:249 1994 10/15/94 10/15/94 R114309 Asc1 UN Asc-1 asc1 Asc001 anterior suture cataract 1 eye (lens or cataract) 8/10/94 R109414 Asc2 UN Asc-2 asc2 Asc002 anterior suture cataract 2 eye (lens or cataract) 8/10/94 R109415 Astt1 UN Astt-1 astt1 Astt001 astroglial cell transcript 1 brain (glial cells) 8/10/94 R109416 Astt2 UN Astt-2 astt2 Astt002 astroglial cell transcript 2 brain (glial cells) 8/10/94 R109417 Astt3 UN Astt-3 astt3 Astt003 astroglial cell transcript 3 brain (glial cells) 8/10/94 R109418 Atfx UN atfx Atfx activating transcription factor X enzyme (DNA or RNA processing) 8/10/94 R109419 Ath2 UN Ath-2 ath2 Ath002 atherosclerosis 2 R viscera (heart or vessels) U U A B A B A U B B U U B B U B A A U B U U U B B B B A U A U B B U U U U U U A U 8/10/94 R109420 Ath6 UN ath6 Ath006 atherosclerosis 6 V Paigen 1993 Jackson Lab Scientific Report 1993 8/10/94 R109421 Ath7 UN ath7 Ath007 atherosclerosis 7 V Paigen 1993 Jackson Lab Scientific Report 1993 8/10/94 R109422 Ath8 UN ath8 Ath008 atherosclerosis 8 V Paigen 1993 Jackson Lab Scientific Report 1993 8/10/94 R109423 Atp5a1 UN Atpm atp5a1, atpm Atp005a001 ATPase, proton transporting, type 5, alpha 1 Mitochondrial F1 complex alpha isoform. Yotov 1993 Biochem Biophy Res Comm 191:142 enzyme (phosphatase) 1993 8/10/94 R109424 Atp5f1 UN apt5f1 Atp005f001 ATP synthase, H+ transporting, mitochondrial F0 complex subunit b, isoform 1 Also referred to as subunit 9, isoform 1. Piko 1994 Biochim Biophys Acta 1194:139 1994 8/10/94 3/24/94 R111561 Atp7a UN atp7a Atp007a ATPase, copper ion transporting, alpha polypeptide Menkes syndrome Mercer 1994 Nature Genet 6:374 1994 8/10/94 8/29/94 R113710 Atpl UN atpl Atpl ATPase-like vacuolar proton channel M64298, M62762 (Hsa) enzyme (phosphatase) 1993 nomenclature 8/10/94 9/10/94 R109425 Av2 UN Av-2 av2 Av002 Abelson virus susceptibility 2 R * syn * s * r r r immune (virus or disease or tumor resistance) C C B C C B C U U U U U U 8/10/94 R109426 Avp-rs1 UN avprs1 Avprs001 arginine vasopressin, related sequence 1 Marini 1993 Genomics 15:200 DNA (pseudogene or related sequence); endocrine (hormone) 1993 8/10/94 R109427 Axd UN axd Axd axial defects Essien 1990 Teratology 42:183 skeleton (vertebrae or ribs); brain (unclassified) 1990 8/10/94 R109428 ba UN 'ba' ba bare No vibrissae at birth. vibrissa extinct? 8/10/94 R109429 Bas UN Hras? bas, hras Bas BALB murine sarcoma oncogene May be the same as Hras. 8/10/94 R109430 Bcei UN bcei Bcei breast cancer, estrogen inducible Lefebvre 1993 J Cell Biol 122:191 V 1993 8/10/94 R109431 Bckdhb UN bckdhb Bckdhb branched chain keto acid dehydrogenase E1, beta Chinsky 1993 Biochim Biophys Acta 1216:499 1993 8/10/94 R109432 Bcp UN bcp Bcp blue cone pigment Chiu 1994 Genomics 21:440 1994 8/10/94 08/05/94 R113711 Bdkrb UN bdkrb Bdkrb bradykinin receptor, beta McIntyre 1993 Mol Pharmacol 44:346 1993 8/10/94 5/11/94 R111807 Bdv1 UN Bdv-1 bdv1 Bdv001 BALB/c strain defective provirus 1 immune (virus or disease or tumor resistance) 8/10/94 R109433 Bgb UN bgb Bgb beta galactosidase, brain Beta-D-galactosidase, brain. brain (brain-specific gene expression); enzyme (unclassified) provisional 8/10/94 R109434 Bh149 UN bh149 Bh149 BH149 Not a sufficiently descriptive name. Improve name. Dickinson 1990 Genomics 6:505 1990 nomenclature 8/10/94 R109435 Bla1 UN bla-1, Bla-1 bla1 bla001 proviral insertion Bla-1 Lohuizen 1991 Cell 65:737 1991 provisional 8/10/94 R109436 Blimp1 UN blimp1 Blimp001 B lymphocyte induced maturation protein 1 100 kDa nuclear protein, transcription factor. Expression is induced during the differentiation of B lymphocytes. Has a Kruppel like zinc finger. Induced by Il2 and Il5. May act on syndecan and on the J chain. Turner AC 1994 Cell 77:297 U08185 1994 8/20/94 8/26/94 R113792 Bmk UN bmk Bmk B cell myeloid kinase Similar to the src-related gene expressed in hemopoietic cells. Holtzman D 1987 PNAS 84:8325 J03023 D enzyme (kinase) 1987 8/10/94 R109437 Brg1 UN brg1 Brg001 brahma related gene 1 Randazzo 1994 Dev Biol 161:229 1993 8/10/94 R109438 Brn3a UN brn3a Brn003a brain 3a, POU domain transcription factor Theil 1993 Nucleic Acids Res 21:5921 1993 8/10/94 R109439 Brn3b UN Brn-3b brn3b, otf Brn003b brain 3b, POU domain transcription factor BRN3B 4 Class 4 POU domain transcription factor expressed in a subset of retinal ganglion cells. In brain found in deep layers of superior colliculus, periaquaductal grey and near area postrema. Distinct from Brn3. Related to human RDC1 gene. Rename O Xiang M 1993 Neuron 11:689 & Theil 1993 Nucleic Acids Res 21:5921 Human sequence: 410 aa ORF, 2 exons. 76% homology to C. elegan's Unc-86 D 1993 old RW personal 8/10/94 R109440 Brn3c UN brn3c Brn003c brain 3c, POU domain transcription factor Theil 1993 Nucleic Acids Res 21:5921 1993 8/10/94 R109441 brp UN brp brp brachypod Japan Goto 1977 Exp Anim 26:231 skeleton (limb or paw or digit) 1977 provisional 8/10/94 R109442 Brp10 UN Brp-1 brp10 Brp010 brain protein 10 * b b b * a b * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109450 Brp11 UN Brp-11 brp11 Brp011 brain protein 11 * b b a * a a * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109451 Brp2 UN Brp-2 brp2 Brp002 brain protein 2 * b b b * b b * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109443 Brp3 UN Brp-3 brp3 Brp003 brain protein 3 * b a b * a a * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109444 Brp4 UN Brp-4 brp4 Brp004 brain protein 4 * a b b * b a * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109445 Brp5 UN Brp-5 brp5 Brp005 brain protein 5 * b b b * b a * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109446 Brp6 UN Brp-6 brp6 Brp006 brain protein 6 * a a a * a a * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109447 Brp7 UN Brp-7 brp7 Brp007 brain protein 7 * a a a * a a * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109448 Brp9 UN Brp-9 brp9 Brp009 brain protein 9 * b b b * a b * brain (brain-specific gene expression); protein (structural) provisional 8/10/94 R109449 Bru UN bru Bru bruised Heterozygotes have enlarged eyes by P30. Cataracts. Males are sterile. Homozygotes die prenatally. eye (unclassified); reproduction (male sterility); lethality (unclassified) 8/10/94 NA R109452 Bsp UN bsp Bsp black spleen Lipofuscin in spleen. Hypostatic to c and p alleles at tyrosinase and p loci. Also to bg and rp genes. Lipofuscin may be affected by genes that affect melanin. Possibly on Chr 7. Crichton DN 1982 Genet Res 39:275 + * * + * Bsp + * color; skin 1982 8/10/94 5/14/94 R109453 bt2 UN bt-2 bt2 bt002 belted 2 Not allelic with bt. color 8/10/94 NA R109454 Btg1 UN btg1 Btg001 B cell translocation gene 1, anti-proliferative Rouault 1993 Gene 129:303 1993 8/10/94 R109455 bus UN bus bus bustling Shoji 1988 Mouse News Lett 81:68 1988 8/10/94 5/22/94 R109456 BVL1 UN BVL-1 bvl1 BVL001 BVL-1 retrotransposon A virus-like (VL30) retrotransposon. Hodgson C 1990 Nucleic Acids Res 18:673 X17124 D 1990 provisional, nomenclature 8/10/94 R109458 C1qa UN c1qa C001qa complement component 1, q subcomponent, a polypeptide 8/10/94 R109459 C1qc UN c1qc C001qc complement component 1, q subcomponent, c polypeptide Petry 1992 Eur J Biochem 209:129 1992 8/10/94 R109461 C58v2 UN C58v-2 c58v2 C058v002 C58 endogenous ecotropic virus 2 immune (virus or disease or tumor resistance) 8/10/94 R109464 C5r1 UN c5r1 C005r001 complement component 5, receptor 1 C5a ligand. Gerard 1992 J Immunol 149:2600 1992 8/10/94 R109462 C6r UN c6r C006r complement component 6, regulatory provisional 8/10/94 R109463 cab UN cab cab cardiac abnormality No glycogen, glucose low, heart muscle. viscera (heart or vessels); lethality (early embryonic) 8/10/94 R109465 cac UN cac cac recessive cataract Developed at 1 month. eye (lens or cataract) 8/10/94 R109466 Caf UN caf Caf caffeine susceptibility brain (unclassified) 8/10/94 R109468 Caga UN caga Caga calgranulin, alpha Initially listed with name Òcalgramin, alphaÓ. Lagasse 1992 Blood 79:1907 1993 reserved 8/10/94 5/9/94 R110635 Cagb UN cagb Cagb calgranulin, beta Initially listed with name calgramin, beta. Lagasse 1992 Blood 79:1907 1993 reserved 8/10/94 5/9/94 R110636 Calna UN Caln calna, caln, can Calna calcineurin, alpha subunit Calmodulin dependent phosphatase. The beta isoform of calcineurin A subunit intereacts with AKAP79 protein. Check whether this locus should have numerical suffixes. In human and rat there are A1 and A2 loci. Kincaid R 1988 PNAS 85:8983 J04134, M31809 (Rno), M29551 (Hsa) Rat and human the sequences from calcineurin A2 1988 nomenclature. 8/10/94 1/22/95 R109469 Calnb UN Caln calnb, caln Calnb calcineurin, beta Calmodulin dependent phosphatase. 8/10/94 R109470 Calnc UN calnc Calnc calcineurin, C Type 3. Calmodulin dependent phosphatase. 8/10/94 R109471 Calr UN calr Calr calreticulin 1993 8/10/94 R109472 Calt UN calt Calt caltractin 20kDa calcium binding protein. Ogawa 1993 Biochim Biophys Acta 1216:126 1993 8/10/94 R109474 Can UN can can cartilage anomaly skeleton (vertebrae or ribs); endocrine (unclassified); lethality (early embryonic) extinct? 8/10/94 R109475 Canx UN canx Canx calnexin 5 Tjoelker LW 1994 Biochemistry 33:3229 L18888 Also sequenced in rat and human. 1994 8/10/94 9/1/94 R111827 Cap1 UN cap1 Cap001 adenylyl cyclase-associated CAP protein 1 yeast gene homolog. In yeast and perhap mammalian cells, Cap and profilin may link growth signals to cytoskeletal/actin alterations. Vojtek 1993 J Cell Sci 105:777 1993 8/10/94 R109476 Cat3 UN Cat-3 cat3 Cat003 dominant cataract 3 Lens opacity. At least 3 alleles at this locus. eye (lens or cataract) 8/10/94 R109478 cb UN 'cb' cb cerebral degeneration Homozygotes are sterile, hydrocephalus. Olfactory bulbs and prosencephalon most affected. No full reports. eye (lens or cataract); brain (unclassified); lethality (early embryonic) 8/10/94 NA R109480 Cbp1 UN Hsp47 cbp1, hsp47 Cbp001 collagen binding protein 1 gp46 or heat shock protein, 47 kD Takechi 1992 Eur J Biochem 206:323 & Clarke 1992 Biochim Biophys Acta 1129:246 & Hosokawa 1993 Gene 126:187 protein (heat shock) 1992 8/10/94 R109482 Cbx-rs2 UN Cbx-rs2 cbxrs2 Cbxrs002 chromobox related sequence 2 Drosophila HP1 class. DNA (homeobox) 8/10/94 R109484 Cbx-rs3 UN Cbx-rs3 cbxrs3 Cbxrs003 chromobox related sequence 3 Drosophila HP1 class. DNA (homeobox) 8/10/94 R109485 Cbx-rs4 UN Cbx-rs4 cbxrs4 Cbxrs004 chromobox related sequence 4 Drosophila HP1 class. DNA (homeobox) 8/10/94 R109486 Cbx2 UN cbx2 Cbx002 chromobox homolog 2 Drosophila Pc class. Pearce 1992 Development 114:921 DNA (homeobox) 1992 8/10/94 R109483 cby UN cby cby chubby Dwarfing, short heads. skeleton (vertebrae or ribs) provisional 8/10/94 R109487 Ccd UN ccd Ccd cleidocranial dysplasia skeleton (vertebrae or ribs); lethality (early embryonic) provisional 8/10/94 R109488 Cd28l UN cd28l, cd281 Cd028l CD28 antigen ligand Selvakumar 1993 Immunogenetics 38:292 1993 8/10/94 5/9/94 R111789 Cd31 UN cd31, pecam1, endocam Cd031 cluster designation 31 antigen Platelet-endothelial cell adhesion molecule 1. Expressed in endothelial cells at intercellular junctions, on platelets, and leukocytes. Related to ICAM1, VCAM1, and NCAM. Involved in endothelial contact, capillary formation, neutrophil transmi Vaporciyan AA 1993 Science 262:1580 immune (cell surface antigen) 8/10/94 R109492 Cd33 UN cd33 Cd033 complement designation 33 antigen gp67 Tehilian 1994 Blood 83:3188 1994 8/10/94 08/05/94 R113712 Cd43ps UN cd43ps Cd043ps cluster designation 43, pseudogene 1993 8/10/94 R109493 Cd63 UN cd63 Cd063 Cd63 antigen melanoma 1 antigen. Miyamoto 1994 BBA 1217:312 1994 8/27/94 8/27/94 R113811 Cd68 UN cd68 Cd068 cluster designation 68 antigen Macrosialin. Holness 1993 J Biol Chem 268:9661 1993 8/10/94 R109494 Cd9 UN cd9 Cd009 cluster designation 9 antigen CD9 Mouse equivalent of human CD9. In humans this is a 24 kDa molecule expressed in platelets and developing B lymphocytes. Rubinstein E 1992 Thrombosis Res 71:377 & Rubinstein E 1993 Genomics 16:132 L08115 1130 nt mRNA sequence; BALB/c kidney. 226 aa antigen. In human the gene is composed of 8 exons spanning about 20 kb. Resembles TAPA1 and CD63 genes. No TATA or CAAT box, but a 120 bp CG rich 5' region with seve D immune (cell surface antigen) 1992 8/10/94 R109489 Cdh11 UN cdh11, obcad Cdh011 cadherin 11 osteoblast type cadherin or OB cadherin. Okazaki 1994 J Biol Chem 269:12092 1994 8/10/94 9/21/94 R111923 Cdk4 UN cdk4 Cdk004 cyclin dependent kinase 4 p34-PSK-J3/cdk4 Matsushime 1992 Cell 71:323 1992 8/10/94 3/24/94 R111507 Cdx2 UN Cdx-2 cdx2 Cdx002 caudal type homeobox 2 DNA (homeobox) 8/10/94 R109496 Cdx4 UN Cdx3, Cdx-3 cdx4, cdx3 Cdx004 caudal type homeobox 4 Symbol and name switched from Cdx3 to Cdx4 per GBASE Broadcast of 3.22.94. DNA (homeobox) 1993 8/10/94 3/23/94 R109497 Cea1 UN Cea-1 cea1 Cea001 carcinoembryonic antigen gene family 1 Rudert F 1992 Mammalian Genome 3:262 immune (antigen) 1992 8/10/94 R109498 Cek7 UN cek7 Cek007 chicken eph/elk receptor like protein tyrosine kinase 7 homolog Zhou 1994 J Neurosci Res 37:129-143 1994 8/27/94 R113925 Cenpa UN cenpa Cenpa centromere autoantigen A Joswig 1991 J Cell Sci 98:37 1991 8/10/94 R109499 Centa UN centa Centa centrosomin A Joswig J 1991 J Cell Sci 98:37 1991 8/10/94 R109500 Cfp2 UN Cfp-2 cfp2 Cfp002 cerebellar folial pattern 2 Q R C57BL/6 and DBA differ in cerebellar folial pattern. Neumann PE 1990 Brain Res 524:85 V brain (cerebellum) D B B D B D B B B D D B D B U D U D D D B D B U U U 1990 1/22/95 1/22/95 R115294 Cfp3 UN Cfp-3 cfp3 Cfp003 cerebellar folial pattern 3 Q R C57BL/6 and DBA differ in cerebellar folial pattern. Neumann PE 1990 Brain Res 524:85 V brain (cerebellum) D B B D B D B B B D D B D B U D U D D D B D B U U U 1990 1/22/95 1/22/95 R115295 cg UN 'cg' cg circumgyrator behavior (unclassified) provisional 8/10/94 R109501 Chat UN chat Chat choline acetyltransferase Ishii 1990 Mol Brain Res 7:151 2.3.1.6 D12486 enzyme (esterase) 1990 8/10/94 10/29/94 R109502 Chd1 UN chd1 Chd001 chromodomain helicase DNA binding protein 1 Delmas 1993 PNAS 90:2414 1993 8/10/94 R109503 Chgc UN chgc Chgc chromogranin C Schimmel 1992 FEBS Lett 314:375 1992 8/10/94 R109504 cho UN cho cho chondrodysplasia Extracellular matrix aberrant. skeleton (vertebrae or ribs); endocrine (unclassified); lethality (early embryonic) 8/10/94 R109505 Chrm1 UN Chrm-1 chrm1 Chrm001 acetylcholine receptor, muscarinic 1, neural Neural. protein (receptor); brain (transmitter or receptor or channel related) 8/10/94 R109506 Chrm4 UN Chrm-4 chrm4 Chrm004 acetylcholine receptor, muscarinic 4 van_Koppen 1993 Biochim Biophys Acta 1173:342 1993 8/10/94 5/22/94 R109507 ci UN 'ci' ci circler behavior (circling) provisional, extinct 8/10/94 R109508 Cip2 UN Cip-2 cip2 Cip002 cold induced protein 2 Jacobsson 1985 JBC 260:16250 1985 8/10/94 R109509 Cip3 UN Cip-3 cip3 Cip003 cold induced protein 3 Jacobsson 1985 JBC 260:16251 1985 8/10/94 R109510 Cip4 UN Cip-4 cip4 Cip004 cold induced protein 4 Jacobsson 1985 JBC 260:16252 1985 8/10/94 R109511 Cip5 UN Cip-5 cip5 Cip005 cold induced protein 5 Jacobsson 1985 JBC 260:16253 1985 8/10/94 R109512 Cip6 UN Cip-6 cip6 Cip006 cold induced protein 6 Jacobsson 1985 JBC 260:16254 1985 8/10/94 R109513 Cip7 UN Cip-7 cip7 Cip007 cold induced protein 7 Jacobsson 1985 JBC 260:16255 1985 8/10/94 R109514 Cip8 UN Cip-8 cip8 Cip008 cold induced protein 8 Jacobsson 1985 JBC 260:16256 1985 8/10/94 R109515 Cip9 UN Cip-9 cip9 Cip009 cold induced protein 9 Jacobsson 1985 JBC 260:16257 1985 8/10/94 R109516 Ck-ps1 UN ckps1 Ckps001 creatine kinase, pseudogene 1 1993 8/10/94 R109518 Ck-ps2 UN ckps2 Ckps002 creatine kinase, pseudogene 2 1993 8/10/94 R109519 Ck-ps3 UN ckps3 Ckps003 creatine kinase, pseudogene 3 1993 8/10/94 R109520 Ckb-rs6 UN Ck-6 ckbrs6 Ckbrs006 creatinine kinase, brain, related sequence 6 R May be on Chr 7. Cho 1991 Mammalian Genome 1:30 enzyme (kinase); DNA (related sequence); brain (unclassified) S S S S S C C C C S S C S C 1991 8/10/94 R109517 cl UN 'cl' cl clubfoot skeleton (vertebrae or ribs); tail kink 8/10/94 R109521 Cle UN cle Cle closed eyes and microophthalmia eye (microophthalmia or anophthalmia) 8/10/94 R109522 clf UN clf clf cleft lip Juriloff 1986 J Craniofac Genet Dev Biol Supp 2:55 skeleton (unclassified) 1986 provisional 8/10/94 R109523 cls UN cls cls coatloss hair provisional 8/10/94 R109528 Cma1 UN cma1 Cma001 chymase 1, mast cell enzyme (unclassified) 8/10/94 R109529 Cma2 UN cma2 Cma002 chymase 2, mast cell enzyme (unclassified) 8/10/94 R109530 Cms UN cms Cms resistance to Coccidioides immitis * s s s * s r * immune (virus or disease or tumor resistance) 8/10/94 R109531 Coc UN coc Coc coralliform cataract eye (lens or cataract) 8/10/94 R109532 Cof UN cof Cof cofilin Moriyama K 1990 Nucleic Acids Res 198:3053 D00472, D00682 (Hsa) 1990 8/10/94 8/29/94 R109533 Col15a1 UN col15a1 Col015a001 procollagen type 15, alpha 1 Abe 1993 Biochem Biphys Res Comm 196:576 1993 8/10/94 R109539 Col4a1 UN Col4a-1 col4a1 Col004a001 procollagen type 4, alpha 1 Basement membrane collagen. Wood L 1988 FEBS Lett 227:5 J03758, X06777 D protein (structural) 1988 8/10/94 R109534 Col4a2 UN Col4a-2 col4a2 Col004a002 procollagen type 4, alpha 2 protein (structural) 8/10/94 R109535 Col8a1 UN Col8a-1 col8a1 Col008a001 procollagen type 8, alpha 1 COL8A1 X66976, X66977 D protein (structural) 1992 8/10/94 10/27/94 R109536 Col9a2 UN Col9a-2 col9a2 Col009a002 procollagen type 9, alpha 2 X63014 D protein (structural) 8/10/94 R109538 Concat UN Cad concat, cad Concat congenital cataract Symbol changed by RW (Mar 94) from Cad to Concat to avoid conflict with the human/univeral symbol CAD used for carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. V eye (lens or cataract) 1993 provisional, nomenclature 8/10/94 3/26/94 R109467 Coombs UN coombs Coombs name unknown R Listed without comment in Map Manager 2.4 files of R. Elliott, Aug 1993. Not in GBASE July 1993. Datta 1982 J Immunol 129:1539 D N N N 8 N 8 U 8 8 N 8 N 8 1982 8/10/94 R109541 Cot UN cot Cot cancer Osaka thyroid oncogene Ohara 1993 Japanese J Cancer Res 84:518 1993 8/10/94 3/24/94 R111508 Cox5b UN cox5b Cox005b cytochrome C oxidase, subunit 5b Basu A 1990 Biochimica Biophysica Acta 1087:98 1.93.1 X53157, M77040, M38201 M77040: 2540 bp genomic sequence. D enzyme (oxidase) 1990 8/10/94 8/9/94 R109542 Cp-rs1 UN Crs-1 cprs1, crs1 Cprs001 cryptdin related sequence 1 Listed twice in July 1993 GBASE as both Crs-1 and Cprs-1. Oullette 1990 JBC 265:9831 DNA (related sequence or pseudogene) 1990 8/10/94 R109548 Cp-rs4 UN Crs-2 cprs4, crs2 Cprs004 cryptdin related sequence 4 Listed twice in July 1993 GBASE as both Crs-4 and Cprs-4. Oullette 1990 JBC 265:9831 DNA (related sequence or pseudogene) 1990 8/10/94 R109550 cpdm UN cpdm cpdm chronic proliferative dermatitis Hogenesch 1993 Am J Pathol 143:972 1993 8/10/94 R109543 Cpl1 UN Cpl-1 cpl1 Cpl001 plasma corticosterone level 1 endocrine (hormone) 8/10/94 R109546 Cpl2 UN Cpl-2 cpl2 Cpl002 plasma corticosterone level 2 endocrine (hormone) 8/10/94 R109547 Cprs1 UN Cprs-1 cprs1 Cprs001 cryptdin related sequence 1 Oullette 1990 JBC 265:9831 8/10/94 R109549 Cpt1 UN cpt1 Cpt001 carnitine palmitoyltransferase 1 CPT Jax Broadcast 1.27.94. Not carnithine but carnitine. Gelb 1993 Genomics 18:651 J05470 (Rno), M58581 (Hsa) 1993 8/10/94 9/17/94 R109551 Cpz UN cpz Cpz chlorpromazine avoidance * * * h * l * * behavior (unclassified) 8/10/94 R109552 Creb UN Crebp1 creb Creb cAMP responsive element binding protein 1 This locus needs a numerical suffix. There is a gene Crebp2 D protein (binding) nomenclature 8/10/94 R109553 Crg2 UN Crg-2 crg2 Crg002 cytokine responsive gene 2 Vanguri 1990 JBC 265:15049 1990 8/10/94 R109554 Crhr UN crhr Crhr corticotropin releaseing hormone receptor Vita 1993 FEBS Lett 335:1 1993 8/10/94 R109555 crhx UN crh crhx, crh crhx cryptothrix Mann SJ 1993 personal communication skin 1993 8/10/94 R109556 Cripto UN MUSCRIPTO cripto Cripto cripto gene homolog Dono R 1992 PNAS 000:000 & Dono R 1993 Development 118:1157 M87321 cripto gene mRNA, complete cds. *Title* The mouse cripto gene: cDNA characterization and expression in the adult mouse and developing embryo D 1992 8/10/94 R109557 Crk1 UN crk1 Crk001 CDC2 related kinase 1 Ershler 1993 Gene 124:305 enzyme (kinase) 1993 8/10/94 R109558 Crk2 UN crk2 Crk002 CDC2 related kinase 2 Ershler 1993 Gene 124:305 enzyme (kinase) 1993 8/10/94 R109559 Crk3 UN crk3 Crk003 CDC2 related kinase 3 Ershler 1993 Gene 124:305 enzyme (kinase) 1993 8/10/94 R109560 Crk4 UN crk4 Crk004 CDC2 related kinase 4 Ershler 1993 Gene 124:305 enzyme (kinase) 1993 8/10/94 R109561 Crk5 UN crk5 Crk005 CDC2 related kinase 5 Ershler 1993 Gene 124:305 enzyme (kinase) 1993 8/10/94 R109562 Crk6 UN crk6 Crk006 CDC2 related kinase 6 Ershler 1993 Gene 124:305 enzyme (kinase) 1993 8/10/94 R109563 crn UN crn crn cranioschisis Homozygotes die shortly after birth. Have anencephalus. May be allele at the oel locus. skeleton (vertebrae or ribs); lethality (early embryonic) 8/10/94 R109564 Cryabp1 UN Crya, bp1 cryabp1, crya, bp1 Cryabp001 crystallin binding protein 1, alpha Not listed in July 1993 GBASE. Status of this locus is unclear to me. Probably equivalent to Crya-1. eye (lens or cataract); protein (structural) 8/10/94 R109565 Crybb2 UN Cryb-2 crybb2, cryb2 Crybb002 crystallin, beta B2 Formerly thought to be on Chr 1. Associated with the Philly mouse mutation, an in-frame deletion of 12 nucleotides. Chambers C 1991 J Biol Chem 266:6742 eye (lens or cataract); protein (structural) 8/10/94 8/29/94 R109566 Crycg UN crycg Crycg crystallin C, gamma Or gamma C crystallin. Graw 1993 Gene 136:145 1993 8/10/94 3/24/94 R111563 Cryz UN cryz Cryz crystallin, zeta quinone reducatase. Gonzalez 1994 Mol Biol Evol 11:305 8/10/94 5/12/94 R111830 Crz UN crz Crz control of early proliferation of T. crusi immune (virus or disease or tumor resistance) provisional 8/10/94 R109567 Csfgr UN csfgr Csfgr colony stimulating factor granulocyte receptor Fukunaga R 1990 Cell 61:341 M58288 protein (receptor) 1990 8/10/94 R109568 Csma UN csma Csma centrosomin A Joswig 1991 J Cell Sci 98:37 1991 8/10/94 R109569 Csnk2a1 UN csnk2a1 Csnk002a001 casein kinase 2, alpha 1 CSNK2A1 20p13 Boldyreff 1992 Biochem Biophys Res Comm 186:723 & Wirkner U 1994 Genomics 19:257 2 Probably maps to mouse Chr 2, perhaps linked to Oxt. enzyme (kinase) 1992 8/10/94 12/15/94 R109570 Csnk2a1-ps1 UN csnk2a1ps1 Csnk002a001ps001 casein kinase 2, alpha 1, pseudogene 1 Boldyreff 1992 Biochem Biophys Res Comm 186:723 M96173 enzyme (kinase); DNA (related sequence or pseudogene) 1992 8/10/94 R109571 Csnk2a1-rs2 UN csnk2a1rs2 Csnk002a001rs002 casein kinase 2, alpha 1, related sequence 2 Boldyreff 1992 Biochem Biophys Res Comm 186:723 M96173 enzyme (kinase); DNA (related sequence or pseudogene) 1992 8/10/94 R109572 Csnk2a1-rs3 UN csnk2a1rs3 Csnk002a001rs003 casein kinase 2, alpha 1, related sequence 3 Boldyreff 1992 Biochem Biophys Res Comm 186:723 M96173 enzyme (kinase); DNA (related sequence or pseudogene) 1992 8/10/94 R109573 Csnk2b UN csnk2b Csnk002b casein kinase 2, beta Also known as phosvitin. 2.7.1.37 X56502, X16312 (Hsa) enzyme (kinase) 8/10/94 9/7/94 R109574 Cspcp UN cspcp Cspcp chondroitin sulfate proteoglycan core protein Baughman 1991 Mol Endocrinol 5:637 protein (glycoprotein) 1991 8/10/94 R109575 Csrp UN csrp Csrp cysteine rich protein Wang1992 J Biol Chem 267:9176 1992 8/10/94 3/24/94 R111564 Cst-rs1 UN Cst-rs1 cstrs1 Cstrs001 cystatin related sequence 1 Epididymal specific. Cornwall 1992 Mol Endocrinol 6:1653 reproduction (sex organ) 1992 8/10/94 R109576 Csx UN csx Csx cardiac specific homeobox Related to the Drosophila homoeobox genes NK3 (bagpipe) and NK4 (tinman) that are expressed in fly heart and gut mesoderm. Komuro I 1993 PNAS 90:8145-8149 D 1993 8/10/94 9/11/94 R109577 ct UN 'ct' ct curly tail Homozygotes have spina bifida, some exencephaly and kinked tail. Vitamin A injections at E8 can increase neuropore defects. skeleton (vertebrae or ribs); tail kink; brain (unclassified) 8/10/94 JR1813 R109578 Cts UN Cs cts, 'cs' Cts cataract and small eye Semidominant mutation with complete penetrance in JCL. ICR strain. Resembles Cat locus, but not tested for allelism. Harata M 1978 Jpn J Genet 53:147 eye (lens or cataract) 1968 provisional 8/10/94 R109579 Ctsb UN ctsb Ctsb cathepsin B A proteinase. Chan S 1986 PNAS 83:7721 X54966, M14222, M14221 (Hsa) 1986 8/10/94 8/29/94 R109580 Ctsl UN ctsl Ctsl cathepsin L Also referred to a preprocathepsin L precursor gene. An abundant transcript induced by transformation of fibroblasts. Joseph LH 1988 J Clin Invest 81:1621 J02583, M20495 (Mmuscaris), X12451 (Hsa) 1413 nt linear dsDNA from Mus muscaris. 334 aa conceptual translation. D 1988 8/10/94 8/29/94 R109582 cu UN 'cu' cu clasper underweight provisional, extinct? 8/10/94 R109583 Cutl1 UN cutl1, cut11 Cutl001 cut-like 1 Homolog of Drosophila cut gene. Valarche 1993 Development 119:881 1993 8/10/94 3/24/94 R111566 cx UN 'cx' cx cerebellal ataxia Author ?? 1966 Mouse News Lett 36:52 brain (cerebellum) provisional, extinct? 8/10/94 5/22/94 R109584 Cyp11d UN cyp11d Cyp011d cytochrome P450, 11d 8/10/94 R109586 Cyp1b1 UN cyp1b1 Cyp001b001 cytochrome P450, 1b1, benz[a]anthracene inducible Sen 1993 PNAS 90:11483 1994 8/10/94 5/24/94 R111891 D0Dnax1 UN d0dnax1 D00Dnax0001 DNA sequence, DNAX Research Institute 1 Brown 1989 J Immunol 142:679 1994 8/10/94 08/05/94 R113754 D0H4S114 UN d0h4s114 D00H04S0114 DNA segment, human D4S114 Studler 1993 Eur J Neurosci 5:614 1994 8/10/94 08/05/94 R113755 D0J1 UN 8d-3.2 d0j1, 8d32 D00J0001 DNA segment, Chr??, Jackson Laboratory 1 R Random amplified polymorphic DNA sequence amplified using a single PCR primer GGGACACYGA. The band is found in C57BL/6. Linked to 9 and 16 at 95%ile. Nadeau 1992 Mammalian Genome 3:55 P DNA (sequence of unknown function) RAPD primer GGGACACYGA U A B A B B B A A B A B B A B B B B A B A B U A A A B B B A A B A B B B A B A B U 1992 8/10/94 R109588 D0Nyu11 UN D12Nyu11 d0nyu11, 12nyu11 D00Nyu0011 DNA segment, Chr unknown, NYU 11 L R S Once thought to map to Chr 12. Now referred to an an unmapped orphan. See 1993 Committee Report. D DNA (sequence of unknown function) 1993 8/10/94 R109589 D1Pas1-rs1 UN d1pas1rs1 D01Pas0001rs01 D1Pas1 related sequence 1 Gee 1994 Gene140:171 1994 8/27/94 R113812 D1Pas1-rs2 UN d1pas1rs2 D01Pas0001rs02 D1Pas1 related sequence 2 Gee 1994 Gene140:171 1994 8/27/94 R113813 Darpp32 UN darpp32 Darpp032 dopamine and cAMP-regulated phosphoprotein, 32 KDa Perez 1992 J Comp Neur 318:304 1992 8/10/94 R109590 Das UN das Das dopamine agonist sensitivity Lush 1981 Gen Pharmacol 12:397 1981 8/10/94 R109591 Dbi UN dbi Dbi diazepam binding inhibitor Owens 1989 Mol Brain Res 6:101 & kato K 1991 J Neurosci 2:704 X61431 1989 8/10/94 R109592 Dci UN dci Dci dodecenoyl-coenzyme A delta isomerase DCI 16p13.3-p13.3 3,2 trans-enoyl-coenzyme A isomerase. A key enzyme in beta oxidation of unsaturated fatty acids in mitochondria. Stoffel 1993 FEBS Lett 333:119 & Janssen U 1994 Genomics 23:223-228 5.3.3.8 Z25821 (Hsa), Z25824 (Hsa) 7 exons spanning 12.5 kb in human. Mouse homologue might be expected to map to Chr 16 or 17. 1964 8/10/94 9/17/94 R111509 Defcr-ps1 UN defcrps1 Defcrps001 defensin related cryptdin pseudogene 1 Huttner 1994 Genomics 19:448-453 1994 8/27/94 R113906 Defcr10 UN Cryp10 defcr10, cryp10 Defcr010 defensin related cryptdin 10 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03061 1994 8/27/94 10/1/94 R113907 Defcr11 UN Cryp11 defcr11, cryp11 Defcr011 defensin related cryptdin 11 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03062 1994 8/27/94 10/1/94 R113908 Defcr12 UN Cryp12 defcr12, cryp12 Defcr012 defensin related cryptdin 12 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03063 1994 8/27/94 10/1/94 R113909 Defcr13 UN Cyrp13 defcr13, cyrp13 Defcr013 defensin related cryptdin 13 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03064 1994 8/27/94 10/1/94 R113910 Defcr14 UN Cryp14 defcr14, cryp14 Defcr014 defensin related cryptdin 14 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03067 1994 8/27/94 10/1/94 R113911 Defcr15 UN Cryp15 defcr15, cryp15 Defcr015 defensin related cryptdin 15 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03065 1994 8/27/94 10/1/94 R113912 Defcr16 UN Cryp16 defcr16, cyrp16 Defcr016 defensin related cryptdin 16 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03066 1994 8/27/94 10/1/94 R113913 Defcr4 UN Cryp4, Cryp04 defcr4, cryp4, cryp04 Defcr004 defensin related cryptdin 4 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03032 1994 8/27/94 10/1/94 R113914 Defcr5 UN Cryp05 defcr5, cryo5, cryp05 Defcr005 defensin related cryptdin 5 Huttner KM 1994 Genomics 19:448-453 U03033 1994 8/27/94 10/1/94 R113915 Defcr6 UN Cryp06 defcr6, cryp6, cryp06 Defcr006 defensin related cryptdin 6 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U12561, U03034 1994 8/27/94 10/1/94 R113916 Defcr7 UN Cryp07 defcr7, cryo7, cryo07 Defcr007 defensin related cryptdin 7 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03036 1994 8/27/94 10/1/94 R113917 Defcr8 UN Cryp08 defcr8, cryp8, cryp08 Defcr008 defensin related cryptdin 8 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03036 1994 8/27/94 10/1/94 R113918 Defcr9 UN Cryp09 defcr9, cryp9, cryp09 Defcr009 defensin related cryptdin 9 Member of a defensin like gene family that codes for cysteine rich peptides in paneth cells. Huttner KM 1994 Genomics 19:448-453 U03037 1994 8/27/94 10/1/94 R113919 Dfp UN dfp Dfp dark foot pads color; tail kink; lethality (early embryonic) 8/10/94 R109594 Dhh UN dhh Dhh desert hedgehog homolog of the Drosophila segment polarity gene hedgehog (hh). Of the three hedgehog genes, Dhh shows the greatest homology to the Drosophila gene. Probably a secreted protein. Echelard 1993 Cell 75:1417 & Smith JC 1994 Cell 76:193 D 1993 old RW personal 8/10/94 5/12/94 R111190 di UN 'di' di duplicate incisors skeleton (teeth, tooth) 8/10/94 R109595 Dipl1 UN dipl1, dipll, dip11 Dipl001 diploid occytes, metaphase I arrested provisional 8/10/94 R109596 Dlk1 UN dlk1 Dlk001 Drosophila dlk-like homolog Laborda 1993 J Biol Chem 268:3817 1993 8/10/94 R109597 Dlx5 UN dlx5 Dlx005 distal-less homeobox homolog 5 Some members of the distal-less homeobox gene family are expressed in developing mouse forebrain. Simeone 1994 PNAS 91:2250 D 1992 reserved 8/10/94 5/24/94 R111894 Dlx6 UN dlx6 Dlx006 distal-less homeobox homolog 6 Some members of the distal-less homeobox gene family are expressed in developing mouse forebrain. Simeone 1994 PNAS 91:2250 D 1994 reserved 8/10/94 5/24/94 R111895 Dmc UN dmc Dmc DMCM susceptibility Seale 1987 1987 provisional 8/10/94 R109598 Dmm UN dmm Dmm disproportionate micromelia Extracellular matrix abnormal. lethality (early embryonic) 8/10/94 R109599 dn UN 'dn' dn deafness Auditory hair cells degenerate by P40. ear (hair; cells or inner ear or hearing impaired); behavior (circling) 8/10/94 R109600 Do UN 'do' Do disoriented Semidominant; now extinct. Heterozygotes behave strangely. Heaving motions, hesitation. brain (unclassified); lethality (early embryonic) 8/10/94 R109601 Domes1 UN domes1 Domes001 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 1 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112529 Domes14 UN domes14 Domes014 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 14 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112536 Domes17 UN domes17 Domes017 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 17 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112537 Domes18 UN domes18 Domes018 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 18 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112538 Domes19 UN domes19 Domes019 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 19 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112539 Domes2 UN domes2 Domes002 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 2 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112530 Domes22 UN domes22 Domes022 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 22 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112540 Domes3 UN domes3 Domes003 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 3 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112531 Domes4 UN domes4 Domes004 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 4 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112532 Domes5 UN domes5 Domes005 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 5 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112533 Domes6 UN domes6 Domes006 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 6 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112534 Domes7 UN domes7 Domes007 glyceraldehyde 3-phosphate dehydrogenase retroprocessed pseudogene 7 One of a family of over 300 GAPDH intronless pseudogenes usually located in heavily methylated, DNAase 1 resistant regions. Garcia-Meunier P 1993 Mammal Genome 4:695 D 1993 RW personal 8/10/94 R112535 Dpep1 UN dpep1 Dpep001 dipeptidase 1, renal Satoh 1993 Biochem Biophys Acta 1163:234 3.4.13.11 1993 8/10/94 R109602 Dsh UN dsh Dsh short digits Homozygotes lack eyes, mouth, ears. Die before E18. skeleton (vertebrae or ribs); tail kink; eye (lens or cataract); ear (hair; cells or inner ear or hearing impaired) 8/10/94 R109604 dup UN dup dup dumpy Oda 1978 Teratology 18:142 V 1978 provisional 8/10/94 R109605 dv UN 'dv' dv dervish Homozygotes circle and are viable. No data on auditory ability. behavior (circling) 8/10/94 R109606 dwg UN dwg dwg dwarf grey Harris 1990 Mouse Genome 86:238 1990 8/10/94 R109607 Ea2 UN Ea-2, H-14 ea2, h14 Ea002 erythrocyte antigen 2 Rho. May be on chr 8. protein (structural) 8/10/94 R109608 Ea3 UN Ea-3 ea3 Ea003 erythrocyte antigen 3 (lambda). * b * b * b * * immune (cell surface antigen) 8/10/94 R109609 Ea5 UN Ea-5, H-5 ea5, 'h5' Ea005 erythrocyte antigen 5 a a * * * * b * immune (cell surface antigen) 8/10/94 R109610 Ea7 UN Ea-7, T ea7, 't' Ea007 erythrocyte antigen 7 a b b b * b b b immune (cell surface antigen) 8/10/94 R109611 Ea8 UN Ea-8 ea8 Ea008 erythrocyte antigen 8 b a * b * a b * immune (cell surface antigen) 8/10/94 R109612 Eaat2 UN eaat2 Eaat002 excitatory amino acid transporter 2 EAAT2 Kirschner MA 1994 Genomics 22:631 U03505 (Hsa) 1994 8/10/94 9/11/94 R113713 Eae UN eae Eae name unknown R Listed without comment in Map Manger 2.4 Aug 1993 files for R. Elliott. Not listed in GBASE July 1993. Knobler 1985 J Neuroimmunol 8:15 J C J J J C C J C U 1985 8/10/94 R109613 ec UN 'ec' ec ectopic Slight developmentally transient increase in eyeball size. Opacity of lens at 5 wks. Posterior part of lens is much thinner than normal. Similar to "lr" locus. eye (lens or cataract) 8/10/94 R109615 ecs UN ecs ecs epistatic circling of SWR/J behavior (circling) 8/10/94 R109616 Ect UN ect Ect E. coli transaminase homolog Niwa 1990 NAR 18:6709 D 1990 8/10/94 R109617 Ect2 UN ect2 Ect002 ect2 oncogene Related to regulators of small GTP-binding proteins. Miki 1993 Nature 363:462 L11316 1993 8/10/94 R109618 Ed UN 'ed' Ed extra digit skeleton (vertebrae or ribs); tail kink 8/10/94 R109619 Edn1 UN edn1 Edn001 endothelin 1 Inoune 1989 PNAS 86:2863 & Kurihara 1994 Nature 368:703 1989 8/10/94 5/12/94 R109620 Edn2 UN edn2, vicp Edn002 endothelin 2 Also known as vasoactive intestinal contractor peptide Saida 1991 Biochem Biophys Acta 1089:404 1989 8/10/94 5/12/94 R111832 Eef2 UN Ef-2 eef2, ef2 Eef002 eukaryotic translation elongation factor 2 M76131, Y07504 (Rno), X51466 (Hsa) M76131: 1179 bp mRNA sequence 1994 8/10/94 8/30/94 R109621 Eef2-ps1 UN Eef2-ps1, Ef2-ps eef2ps1, ef2ps, eef2rs1 Eef002ps001 eukaryotic translation elongation factor 2, pseudogene 1 May be the same as Eef2-rs1 M76175 M76175: 28567 bp genomic sequence nomenclature, duplicate? 8/10/94 8/30/94 R109622 Eef2-rs1 UN Eef2-rs1, Ef2-rs1, Eef2-rs, Eef2l eef2rs1, ef2rs1, eef2rs, eef2l, eef2ps1 Eef002rs001 eukaryotic translation elongation factor 2, related sequence 1 Gene expressed preferentially in MEL cells. Confirm that this is distinct from Eef2-ps1 Yamamoto 19?? nomenclature 8/10/94 8/30/94 R109623 Egp314 UN egp314 Egp0314 epithelial glycoprotein 314 8/10/94 R109626 Eif1a UN Ef1a, Eftu eif1a, ef1a, eftu, eeftu Eif001a eukaryotic translation initiation factor 1, alpha (Tu). Lu X 1989 Nucleic Acids Res 17:442 X13661, M17878, X03688, D 1989 8/10/94 R109627 Eif4a-rs1 UN eif4ars1 Eif004ars001 eukaryotic translation initiation factor 4a, related sequence 1 Gee 1994 Gene140:171 1994 8/27/94 8/27/94 R113814 Eklf UN eklf Eklf erythroid Kruppel-like factor Miller 1993 Mol Cell Bioll 13:2776 1993 8/10/94 R109628 Ela2 UN Ela-2 ela2, ela2a Ela002 elastase 2 This should probably be defined as elastase 2A or IIA X04573, M16652 (Hsa) nomenclature 8/10/94 8/30/94 R109629 Eln UN eln Eln elastin ELN 7q11.1-q21.1 29 24q16-qter 8/10/94 3/27/94 R109630 Em UN 'em' Em Emory cataract Lens opacity by 8 months. eye (lens or cataract) 8/10/94 R109631 Ema UN ema Ema electrophoretic mobility and agglutinability h h h l * l h h blood (anemia) 8/10/94 R109632 Emb-rs4 UN embrs4 Embrs004 embigin related sequence 4 Author ? 1988 Am Soc Biochem Mol Biol 263:3059 D 1988 8/10/94 R109633 Emi1 UN Emi-1 emi1 Emi001 proviral insertion Emi-1 Haupt 1991 Cell 65:753 1991 8/10/94 R109634 Emv10 UN Emv-1 emv10 Emv010 endogenous ecotropic murine leukemia virus 10 b b b b * b b a immune (virus or disease or tumor resistance) 8/10/94 R109640 Emv4 UN Emv-4 emv4 Emv004 endogenous ecotropic murine leukemia virus 4 b b b b * b b b immune (virus or disease or tumor resistance) 8/10/94 R109635 Emv5 UN Emv-5 emv5 Emv005 endogenous ecotropic murine leukemia virus 5 b b b b * b b b immune (virus or disease or tumor resistance) 8/10/94 R109636 Emv6 UN Emv-6 emv6 Emv006 endogenous ecotropic murine leukemia virus 6 b b b b * b b b immune (virus or disease or tumor resistance) 8/10/94 R109637 Emv7 UN Emv-7 emv7 Emv007 endogenous ecotropic murine leukemia virus 7 b b b b * b b b immune (virus or disease or tumor resistance) 8/10/94 R109638 Emv8 UN Emv-8 emv8 Emv008 endogenous ecotropic murine leukemia virus 8 b b b b * b b b immune (virus or disease or tumor resistance) 8/10/94 R109639 Emx1 UN emx1 Emx001 empty spiracles 1 2p14-p13 Homolog of a Drosophila gap gene empty spiracles (ems). In Drosophila this gene has an important role in head segmentation. Contains a homeobox. Expression of Emx1 confined to the mammalian dorsal telencephalon at about E9.5. (see Otx genes) Simeone A 1992 Nature 358:687 & Boncinelli E 1993 J Neurobiol 24:1356 & Kastury K 1994 Genomics 22:41 1992 8/10/94 9/12/94 R109641 Emx2 UN emx2 Emx002 empty spiracles 2 10q26.1-q26.1 Homolog of a Drosophila gap gene empty spiracles (ems). In Drosophila this gene has an important role in head segmentation. Contains a homeobox. Expressed in the dorsal telencephalon and and small parts of the diencephalon starting at E8. (see Otx genes) Simeone A 1992 Nature 358:687 & Boncinelli E 1993 J Neurobiol 24:1356 & Kastury K 1994 Genomics 22:41 Might map to Chr 7, linked to Oat and Mgmt. 1992 8/10/94 9/12/94 R109642 Enc UN enc Enc embyronic nucleus cataract 8/10/94 R109643 Eng UN eng Eng endoglin Ge 1994 Gene 138:201 1994 8/10/94 5/12/94 R111833 Eno3 UN Eno-3 eno3, enob Eno003 enolase 3, beta, muscle 8/10/94 R109645 Eo UN 'eo' Eo eye opacity V 8/10/94 R109646 eob UN eob eob eyelids open at birth Termoto 1988 Exp Anim 37:455 V 1988 8/10/94 R109647 Epa1 UN Epa-1 epa1 Epa001 epidermal antigen 1 protein (receptor); immune (cell surface antigen) 8/10/94 R109648 Epb4.1 UN epb41 Epb004.1 erythrocyte membrane protein band 4.1 Huang 1993 J Biol Chem 268:3758 1993 8/10/94 R109649 epf UN epf epf epileptiform brain (unclassified); brain (epilepsy) 8/10/94 R109650 Eph2 UN eph2 Eph002 epoxide hydrolase 2 Simmons 1985 J Biol Chem 260:515 1994 8/10/94 08/05/94 R113654 epi UN epi epi exocrine pancreatic insufficiency viscera (unclassified) 8/10/94 R109651 Erbal2 UN erbal2, erba12 Erbal002 avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 2 Barnhart 1994 Gene 142:313 1994 8/27/94 8/27/94 R113815 Ercc3 UN Ercc-3 ercc3 Ercc003 excision repair 3 8/10/94 R109652 Erk1 UN erk1 Erk001 elk related tyrosine kinase 1 Ershler 1993 Gene 124:305 enzyme (tyrosine kinase) 1993 8/10/94 R109653 Erk2 UN erk2 Erk002 elk related tyrosine kinase 2 Ershler 1993 Gene 124:305 enzyme (tyrosine kinase) 1993 8/10/94 R109654 Erk3 UN erk3 Erk003 elk related tyrosine kinase 3 Ershler 1993 Gene 124:305 enzyme (tyrosine kinase) 1993 8/10/94 R109655 Es15 UN Es-15 es15 Es015 esterase 15 19 () enzyme (unclassified) 8/10/94 R109656 Es19 UN Es-19 es19 Es019 esterase 19 enzyme (unclassified) provisional 8/10/94 R109657 Esa UN Es-a esa Esa esterase a provisional 8/10/94 R109658 Etl1 UN etl1 Etl001 enhancer trap locus 1 Schoor, Dev Dyn 1993; 197:227-237 1993 8/10/94 R109659 Etsrp71 UN etsrp71 Etsrp071 ets related protein 71 E26 avian erythroblastosis virus leukemia oncogene related protein ER71 Brown T 1992 Genes Development 6:2502 L10426 D 1992 RW personal 8/10/94 10/15/94 R111201, R111943 Etsrp81 UN etsrp81 Etsrp081 ets related protein 81 E26 avian erythroblastosis virus leukemia oncogene related protein ER81 Brown T 1992 Genes Development 6:2502 L10427 D 1992 RW personal 8/10/94 10/15/94 R111202, R111944 exf UN ex exf, 'ex' exf exfoliative Not related to earlier X-zone degeneration locus. skin 8/10/94 R109660 Exz1 UN Exz-1 exz1 Exz001 adrenal x-zone degeneration 1 8/10/94 R109661 Exz2 UN Exz-2 exz2 Exz002 adrenal x-zone degeneration 2 8/10/94 R109662 ey1 UN ey-1 ey1 ey001 eyeless 1 eye (lens or cataract) 8/10/94 R109663 ey2 UN ey-2 ey2 ey002 eyeless 2 eye (lens or cataract) 8/10/94 R109664 Ezg UN ezg Ezg extent of zonular glomerulosa endocrine (unclassified) 8/10/94 R109665 fa UN 'fa' fa falter brain (unclassified); lethality (early embryonic) 8/10/94 R109666 Fabph? UN Fabph-? fabph? Fabph? fatty acid binding protein, heart ? The ? is part of this name. This should probably be changed. Check with GBASE regarding this unusual nomenclature. nomenclature 8/10/94 R109667 Fb UN fb, 'fb' Fb feeble Recessive mutation.. Death by 6 weeks. Low muscle mass. Bermingham N 1994 personal communication 1994 1/22/95 1/22/95 R115291 Fbl UN fbl Fbl fibrillarin A nucleolar protein. Turley SJ 1993 Biochim Biophys Acta 1216:119 Z22593 1127 nt linear rna sequence from BALB/c macrophages. 327 aa conceptual translation. 1993 8/10/94 R109670 Fbp1 UN Fbp-1, Fbp fbp1, fbp, fdp, pfkfb1? Fbp001 fructose bisphophastase 1 Homolog of rat Fbp on rat Chr 17 or may be homolog of rat "6-phosphofructo-2-kinase or fructose-2,6 bisphosphatase, liver and muscle" locus on rat Chr X at Xq22-q31. 17 (FBP OR POSSIBLY PFKFB1) b b b b * b b b enzyme (unclassified) 8/10/94 R109672 Fbp2 UN Fbp-2 fbp2, pfkfb2? Fbp002 fructose bisphophastase 2 Possible homolog of rat "6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase, heart". 13q24.25 (PFKFB2?) * * * * * * a * enzyme (unclassified) 8/10/94 R109673 Fgfa UN fgfa Fgfa fibroblast growth factor, acidic protein (growth factor) 8/10/94 R109674 Fgv2 UN Fgv-2 fgv2 Fgv002 C3H/Fg virus 2 immune (virus or disease or tumor resistance) 8/10/94 R109678 fh UN 'fh' fh fetal hematoma Incomplete penetrance. Fused digits, eyes may be small, corneas opaque. Hemorrhagic blebs on head and feet at E12/13. Like my locus but not allele. Could be allele of "eb" or "bl" loci . 13 tail kink; eye (lens or cataract) 8/10/94 R109679 Fhe UN fhe Fhe Friend helper virus erythroblastosis susceptibility immune (virus or disease or tumor resistance) 8/10/94 R109680 Fk UN 'fk' Fk fleck color; lethality (early embryonic) 8/10/94 R109681 Fkbp1 UN Fkbp fkbp1, fkbp Fkbp001 FK506 binding protein 1, 12 kDa 12 kDa protein. Confirm that thi is the same locus as that sequenced earlier by Nelson. Nelson P 1991 Gene 109:255 & Hendrickson 1993 Gene 134:271 X60203 D 1991 8/10/94 R109682 Fkbp2 UN fkbp2 Fkbp002 FK506 binding protein 1, 13 kDa 13 kDa protein. Check associated between locus and the DNA sequence of Nelson P 1991 Hendrickson 1993 Gene 134:271 1993 8/10/94 R109683 Fkbp4 UN fkbp4 Fkbp004 FK506 binding protein 4 59 kDa protein. Schmitt 1993 Gene 132:267 1993 8/10/94 R109684 Fkh1 UN fkh1 Fkh001 forkhead homolog 1 Drosophila homolog Kaestner 1993 PNAS 90:7628 D 1993 8/10/94 R109685 Fkh2 UN fkh2 Fkh002 forkhead homolog 2 Drosophila homolog Kaestner 1993 PNAS 90:7628 D 1993 8/10/94 R109686 Fkh3 UN fkh3 Fkh003 forkhead homolog 3 Drosophila homolog Kaestner 1993 PNAS 90:7628 D 1993 8/10/94 R109687 Fkh4 UN fkh4 Fkh004 forkhead homolog 4 Drosophila homolog Kaestner 1993 PNAS 90:7628 D 1993 8/10/94 R109688 Fkh5 UN fkh5 Fkh005 forkhead homolog 5 Drosophila homolog Kaestner 1993 PNAS 90:7628 D 1993 8/10/94 R109689 Fkh6 UN fkh6 Fkh006 forkhead homolog 6 Drosophila homolog Kaestner 1993 PNAS 90:7628 D 1993 8/10/94 R109690 fl UN 'fl' fl flipper arm skeleton (vertebrae or ribs); tail kink 8/10/94 R109691 fld UN fld fld fatty liver dystrophy Sweet H 1988 Mouse News Lett 81:69 V 1988 8/10/94 5/22/94 R109692 Flt3l UN flt3l, flt31 Flt003l FMS-like tyrosine kinase 3 ligand Lyman 1993 Cell 75:1157 1993 8/10/94 3/24/94 R111573 fm UN 'fm' fm foan cell reticulosis viscera (unclassified) 8/10/94 R109694 fmt UN fmt fmt formentin Author ?? 1984 Mouse News Lett 70:95 V 8/10/94 5/22/94 R109695 Folbp1 UN Folbp-1 folbp1 Folbp001 folate binding protein 1 Brigle K 1992 J Biol Chem 266:17243 M64782, M97700, M97701 1992 8/10/94 R109696 Folbp2 UN Folbp-2 folbp2 Folbp002 folate binding protein 2 Brigle K 1992 J Biol Chem 266:17243 M64817 1992 8/10/94 R109697 For1 UN For-1 for1 For001 formamidase 1 a * * b * b a * 8/10/94 R109698 For3 UN For-3 for3 For003 formamidase 3 8/10/94 R109699 For4 UN For-4 for4 For004 formamidase 4 8/10/94 R109700 fri UN fri fri frissonant provisional 8/10/94 R109701 Frl UN frl Frl furloss skin; lethality (early embryonic) 8/10/94 R109702 fro UN fro fro fragilitis ossium skeleton (vertebrae or ribs) 8/10/94 R109703 Fshr UN fshr Fshr follicle stimulating hormone receptor 8/10/94 R109704 fsn UN fsn fsn flaky skin 8/10/94 R109705 Fsp27 UN fsp27 Fsp027 fat specific gene 27 Danesch U 1992 J Bio Chem 267:7185 M61737 mRNA sequence 1992 8/10/94 R109706 Fst UN fst, fs344, fs317 Fst follistatin An antagonist of activin beta (Inhba and Inhbb) that displays direct neuralizing activity. A secreted protein that suppresses follicle stimulating hormone secretion. Localized in the Spemann organizer region. Contains a polymorphic microsatellite in the rat. van_den_Eijnden-van Raaij 1992 Genomics 154:356 & Hemmati-Brivanlou A 1994 Cell 77:283 2 Two transcripts generated by differential splicing. P Rat R2 PCR primers, see Kondo Y 1993 Mammalian Genome 4:571 1992 nomenclature 8/10/94 8/23/94 R109707 Ftl1 UN Ftl-1, Ftl, Ftl1 ftl1, ftl, ft11 Ftl001 ferritin, light chain 1 Dugast I 1989 J Bio Chem 264:7498 J04716, K01930 (Rno), M11147 (Hsa) D 1989 8/10/94 8/31/94 R109708 Ftl2 UN Ftl-2, Ftl, Ftl2 ftl2, ftl, ft12 Ftl002 ferritin, light chain 2 8/10/94 R109709 Fv3 UN Fv-3 fv3 Fv003 Friend virus susceptibility 3 Resistance to N- or B-tropic MuLVs. s * * * * r s * immune (virus or disease or tumor resistance) 8/10/94 R109710 Fv5 UN Fv-5 fv5 Fv005 Friend virus susceptibility 5 P-induced early anemia, polycythemia susceptibility. * * p p * * p * immune (virus or disease or tumor resistance) 8/10/94 R109711 Fv6 UN Fv-6 fv6 Fv006 Friend virus susceptibility 6 immune (virus or disease or tumor resistance) 8/10/94 R109712 Fw UN 'fw' Fw fawn Author ?? 1969 Mouse News Lett 40:25 V provisional 8/10/94 5/22/94 R109713 fzt UN fzt fzt fuzzy tail skin; tail kink 8/10/94 R109714 G1-1 UN G1-gene1 g11, g1gene1 G001-001 G1 expressed gene 1 Symbol is non-standard and should be changed by GBASE. RW suggests the simple change to "G1-1". Nikaido 1991 Exp Cell Res 192:102 1991 nomenclature 8/10/94 R109715 G1-2 UN G1-gene2 g12, g1gene2 G001-002 G1 expressed gene 2 Symbol is non-standard and should be changed by GBASE. RW suggests the simple change to "G1-2". Nikaido 1991 Exp Cell Res 192:103 1991 nomenclature 8/10/94 R109716 G1-3 UN G1-gene3 g13, g1gene3 G001-003 G1 expressed gene 3 Symbol is non-standard and should be changed by GBASE. RW suggests the simple change to G1-3. Nikaido 1991 Exp Cell Res 192:104 1991 nomenclature 8/10/94 R109717 G1st UN Gst-1 g1st, gst1 G001st G1 to S transition GTP binding protein 8/10/94 R109718 G22p1 UN g22p1 G022p001 thyroid autoantigen, 70kD Ku antigen. 1.1.1.49 8/10/94 R109720 G6pt UN g6pt G006pt glucose-6-phosphatase Mutations in the human homolog of this gene are associated with von Gierke-5s diesease, an autosomal recessive disease characterized by hepatomegaly, slow growth, hepatic adenomas, hypoglycemia. Shelly 1993 J Biol Chem 268:21482 & Lei KJ 1993 Science 262:580 Human gene spans 12.5 kb, 5 exons, open reading frame of 1071 bp. 357 aa product in human with an endoplasmic reticulum protein retention signal , 6 putative transmembrane regions, 3 potential asparagine-linked glycosylation sites. 1993 8/10/94 3/23/94 R109719 Gabra6 UN Gabra-6 gabra6 Gabra006 gamma aminobutyric acid receptor, alpha 6 5q32-q35 GABA-A subunit. One of at least 13 distinct subunits encoded by separate genes. 8/10/94 7/21/94 R109721 Gabrb2 UN Gabrb-2 gabrb2 Gabrb002 gamma aminobutyric acid receptor, beta 2 GABRB2 5q34-q35 GABA-A subunit. This locus probably maps to Chr 11. 11 8/10/94 10/29/94 R109722 Gabrd UN gabrd Gabrd gamma aminobutyric acid receptor, delta GABA-A subunit. Sommer B 1990 DNA Cell Bio 9:561 M60587, M60588, M60589, M60591, M60592, M60593, M60594, M60595, M60596 Sequences of 9 exons. D 1990 8/10/94 R109723 Gabt1 UN Gabt gabt1, gabt, gat1 Gabt001 gamma amino butyric acid transporter 1 A family of genes. Liu Z 1992 PNAS 89:6639 M92377, M92378, M97632 D 1992 8/10/94 R109725 Gabt2 UN gabt2, gat2 Gabt002 gamma amino butyric acid transporter 2 A family of genes. Liu Z 1992 PNAS 89:6639 1992 8/10/94 R109726 Gabt3 UN gabt3 gat3 Gabt003 gamma amino butyric acid transporter 3 A family of genes. Liu Z 1992 PNAS 89:6639 L04663 1992 8/10/94 R109727 Gabt4 UN gabt4, gat4 Gabt004 gamma amino butyric acid transporter 4 A family of genes. Liu Z 1992 PNAS 89:6639 L04662 1992 8/10/94 R109728 Gam UN gam Gam gammy Abnormal morphology of a signel hindlimb. Flexed toes. Resembles human focal hystonic syndromes. Bermingham N 1994 personal communication 1994 1/22/95 1/22/95 R115293 Gapd-ps1 UN Gapd-ps gapdps1, gapdps Gapdps001 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 1 Galland 1990 Biochimie 72:759 D 1990 8/10/94 R109729 Gapd-ps10 UN gapdps10 Gapdps010 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 10 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109738 Gapd-ps11 UN gapdps11 Gapdps011 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 11 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109739 Gapd-ps12 UN gapdps12 Gapdps012 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 12 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109740 Gapd-ps2 UN gapdps2 Gapdps002 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 2 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109730 Gapd-ps3 UN gapdps3 Gapdps003 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 3 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109731 Gapd-ps4 UN gapdps4 Gapdps004 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 4 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109732 Gapd-ps5 UN gapdps5 Gapdps005 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 5 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109733 Gapd-ps6 UN gapdps6 Gapdps006 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 6 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109734 Gapd-ps7 UN gapdps7 Gapdps007 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 7 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109735 Gapd-ps8 UN gapdps8 Gapdps008 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 8 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109736 Gapd-ps9 UN gapdps9 Gapdps009 glyceraldehyde 3-phosphate dehydrogenase, pseudogene 9 Garcia-Meunier 1993 Mammalian Genome 4:695 1993 8/10/94 R109737 Gapds UN Gapd-s gapds Gapds glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Testis specific. Welch J 1992 Bio Reproduct 46:869 M60978 D 1992 8/10/94 R109741 Gata2 UN Gata-2 gata2 Gata002 GATA DNA binding protein 2 Zon 1991 J Biol Chem 266:22948 1991 8/10/94 8/31/94 R109742 Gata4 UN Gata-4 gata4 Gata004 GATA DNA binding protein 4 A retinoic acid inducible GATA-binding transcription factor that is expressed in heart, intestinne, liver, primitive endoderm, and gonads. Wilson D 1993 Mol Cell Biol 13:2235 & Arceci 1993 Mol Cell Bioll 13:2235 X55123 D 1993 8/10/94 8/31/94 R109744 Gbp2 UN Gbp-2 gbp2 Gbp002 guanine nucleotide-binding protein 2 Wynn 1991 J Immunol 147:4384 1991 8/10/94 R109745 Gcap8 UN gcap8 Gcap008 granule cell antiserum positive 8 Kambouris 1993 Mol Brain Res 18:321 brain (cerebellum) 1993 8/10/94 R109746 Gcd UN gcd Gcd germ cell deficient Transgene insert site. 1993 transgene 8/10/94 R109747 Gcdp UN gcdp Gcdp granule cell differentiation protein Taoka 1994 J Biol Chem 269:9946 1994 8/10/94 08/05/94 R113714 Gcgr UN gcgr Gcgr glucagon receptor Campos 1994 Endocrinology 134:2156 1994 8/27/94 R113900 Gch UN gch Gch GTP cyclohydrolase 1 3.5.4.16 8/10/94 R109748 Gda UN gda Gda guanine deaminase Deaminates guanine to xanthine and ammonia. Formerly called guanase. 3.5.4.3 enzyme (unclassified) 8/10/94 9/8/94 R109749 Gdcr1 UN Gdcr-1 gdcr1 Gdcr001 glycerol phosphate dehydrogenase regulator 1 High in cerebellum of BALB/c, low in C57BL/6. brain brain (unclassified); enzyme (unclassified) 8/10/94 R109750 Gdcr2 UN Gdcr-2 gdcr2 Gdcr002 glycerol phosphate dehydrogenase regulator 2 brain (unclassified); enzyme (unclassified) 8/10/94 R109751 Gdf1 UN Gdf-1 gdf1 Gdf001 growth differentiation factor 1 8/10/94 R109752 Gdf9 UN Gdf-9 gdf9 Gdf009 growth differentiation factor 9 McPherron 1993 J Biol Chem 268:3444 1993 8/10/94 R109753 Gdi1 UN gdi1 Gdi001 glycerolphosphate dehydrogenase dissociation inhibitor 1 Shisheva 1994 Mol Cell Biol 14:3459 1994 10/15/94 10/15/94 R114319 Gdi2 UN gdi2 Gdi002 glycerolphosphate dehydrogenase dissociation inhibitor 2 Shisheva 1994 Mol Cell Biol 14:3459 1994 10/15/94 10/15/94 R114320 gdn UN gdn gdn golden color 8/10/94 R109754 Gdr1 UN Gdr-1 gdr1 Gdr001 G6PD regulator 1 May be linked to brown locus on chr 4. l h l l * l l l enzyme (unclassified) 8/10/94 R109755 Gdr2 UN Gdr-2 gdr2 Gdr002 G6PD regulator 2 May be on chr 4. 8/10/94 R109756 Gem UN gem Gem GTP binding protein (gene overexpressed in skeletal muscle) Maguire 1994 Science 265:241 1994 10/15/94 10/15/94 R114321 Gfpt UN gfpt Gfpt glutamine-fructose-6-phosphate transaminase Sayeski 1994 Gene 140:289 1994 8/10/94 5/12/94 R111834 Gfrp UN gfrp Gfrp growth factor response protein May be related to the growth factor-inducible protein, Pip92, a short-lived protein in PC12 cells (see GenBank M59821) 8/10/94 R109757 ggld UN ggld ggld gamma globulin 1 deficiency 8/10/94 R109758 Ggm2 UN Ggm-2 ggm2 Ggm002 gangliosidase expression 2 enzyme (unclassified) 8/10/94 R109759 Ggtbi UN Ggtb-i ggtbi Ggtbi glycoprotein 4-beta galactosyltransferase influence locus Lopez 1988 BBRC 156:1223 1988 8/10/94 R109760 Gir UN gir Gir glucocorticoid induced receptor 8/10/94 R109761 Glif UN glif Glif glycosylation-inhibiting factor Mikayama 1993 PNAS 90:10056 1994 8/10/94 08/05/94 R113715 Glnf UN glnf Glnf GLN retrotransposon family Symbol and name should be modified to fit in with other GLN family members. Obata 1988 J Virol 62:4381 1988 nomenclature 8/10/94 R109763 Glns-ps2 UN Glns-ps2 glnsps2 Glnsps002 glutamine synthetase pseudogene 2 8/10/94 R109765 Glo2 UN Glo-2, Hagh glo2, hagh Glo002 glyoxalase 2 Hom HAGH 16p13.3 Once knonwn as hydroxyacyl glutathione hydrolase. Mapped in human and rat. Homologous mouse locus may map to Chr 11 (RW Mar 94). Tan 1993 Biochem Genet 31:473 2 1993 8/10/94 8/18/94 R109766, R110780 Glp1r UN glp1r Glp001r glucagon like peptide 1 Campos 1994 Endocrinology 134:2156 1994 8/27/94 R113901 Glut UN glut Grm008 glucose transporter Relation to numbered Glut loci is unclear. Symbol may need to be changed. M13979 (Rno), K03195 (Hsa) nomenclature 8/10/94 8/31/94 R109786 Glyt1 UN Glyt-1 glyt1 Glyt001 glycine transporter 1 Liu Q 1992 FEBS Lett 305:110 X67056 D 1992 8/10/94 R109767 Gm2a UN gm2a Gm002a ganglioside >M2< activator protein Hom GM2A 5q31.1-q33.1 Bellachioma 1993 Biochem J 294:227 & Heng HH 1993 Genomics 18:429 1993 old RW personal 8/10/94 8/18/94 R111547 Gmem UN gmem Gmem glial mesenchymal extracellular matrix glycoprotein Weller 1991 J Cell Biol 112:355 brain (glial cell); protein (glycoprotein) 1991 8/10/94 R109768 Gmt1 UN gmt1 Gmt001 glutamate transporter 1 Tanaka 1993 Neurosci Lett 159:183 1994 8/10/94 R111946 Gna0 UN Gna-0 gna0 Gna0 guanine nucleotide binding protein, alpha 0 G protein, G-0-alpha. Not listed in GBASE, July 1993. Strathmann 1989 PNAS 86:7407 & Murtagh J 1991 Mol Cel Bio 11:1146 M59929 D 1989 8/10/94 R109769 Gna10 UN Gna-10 gna10 Gna010 guanine nucleotide binding protein, alpha 10 G protein. Strathmann 1989 PNAS 86:7407 M57635 1989 8/10/94 R109770 gnd UN gnd gnd generalized neuroaxonal dystrophy 8/10/94 R109772 Gnrhp UN gnrhp Gnrhp gonadotropin releasing hormone associated protein Mason 1986 Science 234:1366 M14872 1986 8/10/94 R109773 gp UN 'gp' gp gaping lids Eyes open at birth, eyes become opaque, lens is about twice normal size. eye (lens or cataract) 8/10/94 R109775 Gp42 UN gp42 Gp042 glycoprotein 42 Ig superfamily member. Alltruda 1989 Gene 85:445 1989 8/10/94 R109776 Gp70 UN gp79 Gp070 glycoprotein 70 8/10/94 R109777 Gpcr10 UN gpcr10 Gpcr010 G protein coupled receptor 10 Wilkie T 1994 Genomics 18:175-184 1994 8/27/94 R113924 Gpcr20 UN gpcr20 Gpcr020 G protein coupled receptor 20 Saeki 1993 FEBS Lett 336:317-322 1994 8/27/94 R113920 Gpcr21 UN gpcr21 Gpcr021 G protein coupled receptor 21 Saeki 1993 FEBS Lett 336:317-322 1994 8/27/94 R113921 Gpe1bp UN gpe1bp Gpe001bp granulocyte colony stimulating factor promoter element 1 binding protein 8/10/94 R109779 Grg UN grg Grg related to Drosophila groucho gene Mallo, Mech Dev 1993; 42:67 1993 8/10/94 R109780 gri UN gri gri grey intense Davisson MT 1994 personal communication 1994 8/10/94 5/11/94 R111808 Grid1 UN grid1 Grid001 glutamate receptor ionotropic, delta 1 Kuramoto T 1994 personal communication 1994 8/10/94 R109781 Grik4 UN grik4 Grik004 glutamate receptor, ionotropic, kainate 4 Kainate responsive, non-NMDA (N-methyl-D-aspartate) type glutatmate receptor. Kuramoto T 1994 personal communication 1994 8/10/94 R109782 Grin2a UN grin2a Grin002a glutamate receptor, ionotropic, NMDA 2A, epsilon 1 N-methyl-D-aspartate responsive receptor. Natural ligand is glutamate. Kuramoto T 1994 personal communicaton 1994 8/10/94 R109783 Grin2c UN grin2c Grin002c glutamate receptor, ionotropic, NMDA 2C, epsilon 3 N-methyl-D-aspartate responsive receptor. Natural ligand is glutamate. Kuramoto T 1994 personal communicaton 1994 8/10/94 R109784 Grin2d UN grin2d Grin002d glutamate receptor, ionotropic, NMDA 2D, epsilon 4 N-methyl-D-aspartate responsive receptor. Natural ligand is glutamate. Kuramoto T 1994 personal communicaton 1994 8/10/94 R109785 Grn UN grn Grn granulin Baba, FEBS Lett 1993; 322:89 1993 8/10/94 R109787 Grp58 UN grp58 Grp058 glucose regulated protein, 58 kDa Mazzarella 1994 Arch Biochem Biophys 308:454 1994 8/10/94 3/24/94 R111576 Grp94 UN grp94 Grp094 glucose regulated protein 94 kD Kim 1990 Differentiation 42:153 & Lee 1983 JBC 258:597 1983 8/10/94 R109788 gs UN gs 'gs', glab gs glabrous Change symbol to Glab to avoid conflict with Gs (greasy). provisional, nomenclature 8/10/94 10/16/94 R109789 Gsc UN Goosecoid, MUSHOMBXA gsc, goosecoid Gsc goosecoid homeobox protein GSC 14q32.1 DNA binding protein with specificity similar to Drosophila bicoid product. Induced by peptide growth factor, activin, in the Spemann organizer of Xenopus. Has a role in gastrulation in the mouse. Dose-dependent mesodermal differentiation in X Blum M 1992 Cell 69:1097 & Gaunt 1993 Development 117:769 & Niehrs C 1994 Science 263:817 & Blum M 1994 Genomics 21:388 M85271 Complete cds D 1992 8/10/94 7/22/94 R109790 Gsl8 UN gsl8, gs18 Gsl008 glycolipid expression 8 Suzuki A 1994 personal communication 1994 8/10/94 R109791 Gsta2-rs2 UN Gsta2-rs2, Gst-2.2 gsta2rs2, gst22 Gsta002rs002 glutathione S-transferase, alpha 2, related sequence 2 R Symbol should probably be changed to Gst2-rs2. Not in GBASE July 1993 as an alias or as a principal. Listed in Map Manager files August 1993. Kasahari 1990 Genomics 8:90 C B C B C B C C C B C B C 1990 8/10/94 R109792 Gstars UN Gsta-rs gstars Gstars glutathione S-transferase, Ya subunit, related sequence 8/10/94 R109793 Gstb-rs1 UN gstbrs1 Gstbrs001 glutathione S-transferase Yb, related sequence 1 Reinhart 1993 Arch Biochem Biophys 303:383 1993 8/10/94 5/11/94 R111809 Gstb1 UN Gstb-1 gstb1 Gstb001 glutathione S-transferase, Yb1 subunit 8/10/94 R109794 Gstb2 UN Gstb-2 gstb2 Gstb002 glutathione S-transferase, Yb2 subunit 8/10/94 R109795 Gstb4 UN Gstb-4 gstb4 Gstb004 glutathione S-transferase, Yb4 subunit 8/10/94 R109796 Gstc2 UN Gstc-2 gstc2 Gstc002 glutathione S-transferase, Yc2 subunit 8/10/94 R109797 Gv1 UN Gv-1 gv1 Gv001 Gross virus antigen 1 a a a b * b a a immune (cell surface antigen) 8/10/94 R109798 Gypa UN gypa Gypa glycophorin A An erythroid specific membrane protein. Matsui Y 1989 Gene 77:325 M26385, M73815 D 1989 8/10/94 R109799 H10 UN H-1 h10 H010 histocompatibility 10 immune (cell surface antigen) 8/10/94 R109801 H11 UN H-11 h11 H011 histocompatibility 11 immune (cell surface antigen) 8/10/94 R109802 H12 UN H-12 h12 H012 histocompatibility 12 b ^ #NAME? a * a a #NAME? immune (cell surface antigen) 8/10/94 R109803 H26 UN H-26 h26 H026 histocompatibility 26 immune (cell surface antigen) 8/10/94 R109804 H41 UN H-41 h41 H041 histocompatibility 41 * b b b * b b * immune (cell surface antigen) 8/10/94 R109805 H48 UN H-48 h48 H048 histocompatibility 48 8/10/94 R109806 H9 UN H-9 'h9' H009 histocompatibility 9 * a * b * #NAME? #NAME? immune (cell surface antigen) 8/10/94 R109800 HaA10 UN Ha-A1 haa10 HaA010 hemopoietic cell anitgen 114/A10 Dougherty 1989 J Biol Chem 264:6509 1989 8/10/94 R109807 Hacl1 UN hacl1 Hacl001 hair follicle specific gene 1 IFAP keratin family member Huh 1994 J Invest Dermatol 102:716 1994 8/10/94 08/05/94 R113716 Had1 UN Had-1 had1 Had001 hemadsorption decrease 1 8/10/94 R109808 Hat1 UN Hat-1 hat1 Hat001 histidine aminotransferase 1 enzyme (unclassified) 8/10/94 R109809 hbd UN hbd hbd hemoglobin deficient blood (anemia) 8/10/94 R109810 Hcm UN hcm Hcm heterochromatin, mutliple chromosomes Is this a locus? Check with GBASE regarding status Oct 1993. 8/10/94 R109811 hcp UN hcp hcp hypochondrodysplasia provisional 8/10/94 R109812 Hct UN hct Hct hair constriction skin 8/10/94 R109813 hea UN hea hea hereditary erythroblastic anemia Arose on CF-1 mice. Homozygotes are yellow. Die by P20. Many nucleated RBCs. color; blood (anemia) 8/10/94 R109814 Hegfl UN hegfl, hbnf Hegfl heparin binding epidermal growth factor-like growth factor Check relation to heparin-binding neurotropic factor on Chr 6. Abraham 1993 Biochem Biophys Res Comm 190:125 M63503, M35718 (Hsa) 1993 8/10/94 10/27/94 R109815 Hfh1 UN hfh1 Hfh001 HNF-3/forkhead homolog 1 Clevidence 1993 PNAS 90:3948 10/5/94 R114425 Hfh2 UN hfh2 Hfh002 HNF-3/forkhead homolog 2 Clevidence 1993 PNAS 90:3948 10/5/94 R114426 Hfh3 UN hfh3 Hfh003 HNF-3/forkhead homolog 3 Clevidence 1993 PNAS 90:3948 10/5/94 R114427 Hfh4 UN hfh4 Hfh004 HNF-3/forkhead homolog 4 Clevidence 1993 PNAS 90:3948 10/5/94 R114428 Hfh5 UN hfh5 Hfh005 HNF-3/forkhead homolog 5 Clevidence 1993 PNAS 90:3948 10/5/94 R114429 Hfh6 UN hfh6 Hfh006 HNF-3/forkhead homolog 6 Clevidence 1993 PNAS 90:3948 10/5/94 R114430 Hfh7 UN hfh7 Hfh007 HNF-3/forkhead homolog 7 Clevidence 1993 PNAS 90:3948 10/5/94 R114431 Hfh8 UN hfh8 Hfh008 HNF-3/forkhead homolog 8 Clevidence 1994 Dev Biol 00:000 10/5/94 R114432 Hfhbf1 UN hfhbf1 Hfhbf001 HNF-3/forkhead homolog, brain factor 1 Tao 1992 Neuron 8:957 10/5/94 11/5/94 R114433 Hfhbf2 UN hfhbf2 Hfhbf002 HNF-3/forkhead homolog, brain factor 2 Clevidence 1993 PNAS 90:3948 10/5/94 11/5/94 R114434 Hfhbf3 UN hfhbf3 Hfhbf003 HNF-3/forkhead homolog, brain factor 3 Clevidence 1993 PNAS 90:3948 10/5/94 11/5/94 R114435 Hfi UN hfi Hfi hydropic fibers 8/10/94 R109817 Hgh3 UN Hgh-3 hgh3 Hgh003 human growth hormone 3 Site of human growth hormone insertion. Is this site significant, or is this just a human transgene?. endocrine (hormone) transgene 8/10/94 R109820 Hgh4 UN Hgh-4 hgh4 Hgh004 human growth hormone 4 Site of human growth hormone insertion. endocrine (hormone) transgene 8/10/94 R109821 Hgl UN hgl Hgl heregulin Meyer 1994 PNAS 91:1064 1994 8/10/94 3/24/94 R111575 Hhex UN hhex Hhex hematopoietically expressed homeobox Bedford 1993 Nuclei Acids Res 21:1245 DNA (homeobox); blood (unclassified) 1993 8/10/94 R109822 Hi UN 'hi' Hi hare tail provisional 8/10/94 R109823 hid UN hid hid hair interior defect skin 8/10/94 R109824 Hiomt UN hiomt Hiomt hydroxylindole-O-methyltransferase Needed for melatonin synthesis in pineal gland, important for diurnal rhythm. * * l l * l * * color; brain (unclassified); enzyme (unclassified) 8/10/94 R109825 Hist? UN hist? Hist? histone, H4 Yes, the "?" is part of the formal symbol. Confirm with GBASE. Meier 1989 NAR 17:795 1989 nomenclature 8/10/94 R109827 Hist-ps UN Hist-ps, Hist1-3.3ps? histps Histps histone 3.3, pseudogene Compare to Hist1-3.3ps locus which has the same name. Check with GBASE regarding status. duplicate?, nomenclature 8/10/94 R109828 Hist1-3.3-ps UN Hist-ps?, Hist3.3-ps hist133ps, hist33ps Hist001-003.3ps histone 3.3, pseudogene Compare to Hist-ps locus which has the same name. Check withy GBASE regarding status. nomenclature 8/10/94 R109826 Hkr1 UN Hkr-1 hkr1 Hkr001 GLI-Kruppel family member HKR1 May be the same locus at zinc finger protein 5. 8/10/94 R109829 Hld UN hld Hld hippocampal lamination defect Dominant or semidominant. In Balb/c the hippocampal the older cells are deeper. Backwards. brain (unclassified) 8/10/94 R109830 Hmbpr UN hmbpr Hmbpr hemopoietic myelin basic protein 8/10/94 R109831 Hmg2 UN hmg2 Hmg002 high mobility group protein 2 D 8/10/94 R109832 Hmox1 UN hmox1, heox Hmox001 heme oxygenase 1 HMOX1 22q12 Decycling. An inducible heme oxygenase. It is the rate limiting enzyme in the heme degradative pathway. Products are biliverdin and carbon monoxide. A heat shock protein that may protect neurons in specific parts of the brain. Important role in protection against oxidative stress. Alam 1992 J Biol Chem 267:21894 & Kutty RK 1994 Genomics 20:513 & Ewing JF 1991 PNAS 88:5364 19 (HEOX) 1.14.99.3 J02722 (Rno), X06985 (Hsa) 1992 8/10/94 9/10/94 R109834 Hnrpk UN hnrpk Hnrpk heterogeneous nuclear ribonucleoprotein K Ostrowski 1994 J Biol Chem 269:17626 10/5/94 R114436 Hnrpx UN hnrpx Hnrpx heterogeneous nuclear ribonucleoprotein X Hahm 1993 Nucleic Acids Res 21:3894 1993 8/10/94 5/12/94 R111837 hpc UN hpc hpc hyperspiny Purkinje cell Both sexes sterile, dendritic regression, not much cell death. brain (cerebellum) 8/10/94 R109835 Hpd UN Hppd hpd, hppd Hpd 4-hydroxyphenyl pyruvic acid dioxygenase enzyme (unclassified) 8/10/94 R109836 hph2 UN hph-2 hph2 hph002 hyperphenylalaninemia 2